Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | /Acetyltransf_4(toxin) |
Location | 2050290..2051798 | Replicon | chromosome |
Accession | NZ_CP116725 | ||
Organism | Pseudomonas aeruginosa strain 2881 |
Toxin (Protein)
Gene name | - | Uniprot ID | Q9HYX1 |
Locus tag | PMJ88_RS09730 | Protein ID | WP_003119682.1 |
Coordinates | 2050290..2050877 (+) | Length | 196 a.a. |
Antitoxin (Protein)
Gene name | - | Uniprot ID | A6V2F0 |
Locus tag | PMJ88_RS09735 | Protein ID | WP_012074952.1 |
Coordinates | 2050944..2051798 (+) | Length | 285 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
PMJ88_RS09725 (PMJ88_09725) | 2046545..2050024 | - | 3480 | WP_003117605.1 | PAS domain-containing hybrid sensor histidine kinase/response regulator | - |
PMJ88_RS09730 (PMJ88_09730) | 2050290..2050877 | + | 588 | WP_003119682.1 | GNAT family protein | Toxin |
PMJ88_RS09735 (PMJ88_09735) | 2050944..2051798 | + | 855 | WP_012074952.1 | AraC family transcriptional regulator | Antitoxin |
PMJ88_RS09740 (PMJ88_09740) | 2051894..2054059 | + | 2166 | WP_272226837.1 | TonB-dependent receptor family protein | - |
PMJ88_RS09745 (PMJ88_09745) | 2054234..2056108 | + | 1875 | WP_003117607.1 | MFS transporter | - |
PMJ88_RS09750 (PMJ88_09750) | 2056169..2056378 | - | 210 | WP_003115568.1 | cold-shock protein | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
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Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 196 a.a. Molecular weight: 21901.23 Da Isoelectric Point: 9.8676
>T269203 WP_003119682.1 NZ_CP116725:2050290-2050877 [Pseudomonas aeruginosa]
MSRRAPMFKPLPITLQRGALRLEPLVEADIPELVSLAEANREALQYMDGPTRPDWYRQSLAEQREGRALPLAVRLGVQLV
GTTRFAEFLPALPACEIGWTWLDQAQHGSGLNRMIKYLMLKHAFDNLRMVRVQLSTAASNLRAQGAIDKLGAQREGVLRN
HRRLAGGRLDDTFVYSITDHEWPQVKAALEASFTG
MSRRAPMFKPLPITLQRGALRLEPLVEADIPELVSLAEANREALQYMDGPTRPDWYRQSLAEQREGRALPLAVRLGVQLV
GTTRFAEFLPALPACEIGWTWLDQAQHGSGLNRMIKYLMLKHAFDNLRMVRVQLSTAASNLRAQGAIDKLGAQREGVLRN
HRRLAGGRLDDTFVYSITDHEWPQVKAALEASFTG
Download Length: 588 bp
Antitoxin
Download Length: 285 a.a. Molecular weight: 31788.11 Da Isoelectric Point: 7.7066
>AT269203 WP_012074952.1 NZ_CP116725:2050944-2051798 [Pseudomonas aeruginosa]
VPDETSGEHTHFWRAAELGGVELLHARYVEQRFAPHVHSGFALVFIEQGAQRFRHRGGEHLAPWGSMVLINPDEVHTGSK
AHDSGWLYRGYYPEVEQIASILDELEIRHGGVPRFADSVVHDQPLARAFVHLHRLLADHAGSLETQTCWRETLLALFRRH
ARLPEAPKAGSEPLAVARARELLAARLLDPPSLEELAAAVNLSPFHFARVFRRATGMPPHAWLRQRRLEQARALLKNGRA
PLDVALELGFADQSHLGRQFKQAYGVAPGEYRAACARSSLTMCE
VPDETSGEHTHFWRAAELGGVELLHARYVEQRFAPHVHSGFALVFIEQGAQRFRHRGGEHLAPWGSMVLINPDEVHTGSK
AHDSGWLYRGYYPEVEQIASILDELEIRHGGVPRFADSVVHDQPLARAFVHLHRLLADHAGSLETQTCWRETLLALFRRH
ARLPEAPKAGSEPLAVARARELLAARLLDPPSLEELAAAVNLSPFHFARVFRRATGMPPHAWLRQRRLEQARALLKNGRA
PLDVALELGFADQSHLGRQFKQAYGVAPGEYRAACARSSLTMCE
Download Length: 855 bp
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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