Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | /Xre(antitoxin) |
Location | 5093653..5094911 | Replicon | chromosome |
Accession | NZ_CP116722 | ||
Organism | Pseudomonas aeruginosa strain 2868 |
Toxin (Protein)
Gene name | - | Uniprot ID | V6AJ34 |
Locus tag | PMJ90_RS24235 | Protein ID | WP_003086331.1 |
Coordinates | 5093653..5094408 (-) | Length | 252 a.a. |
Antitoxin (Protein)
Gene name | - | Uniprot ID | V6AJU7 |
Locus tag | PMJ90_RS24240 | Protein ID | WP_003086329.1 |
Coordinates | 5094543..5094911 (-) | Length | 123 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
PMJ90_RS24225 (PMJ90_24225) | 5088824..5091367 | + | 2544 | WP_033955245.1 | acyl-homoserine-lactone acylase QuiP | - |
PMJ90_RS24230 (PMJ90_24230) | 5091523..5092884 | - | 1362 | WP_003120632.1 | DNA recombination protein RmuC | - |
PMJ90_RS24235 (PMJ90_24235) | 5093653..5094408 | - | 756 | WP_003086331.1 | RES family NAD+ phosphorylase | Toxin |
PMJ90_RS24240 (PMJ90_24240) | 5094543..5094911 | - | 369 | WP_003086329.1 | DUF2384 domain-containing protein | Antitoxin |
PMJ90_RS24245 (PMJ90_24245) | 5094984..5096270 | - | 1287 | WP_003086327.1 | FAD-binding oxidoreductase | - |
PMJ90_RS24250 (PMJ90_24250) | 5096326..5097915 | - | 1590 | WP_023464367.1 | aldehyde dehydrogenase family protein | - |
PMJ90_RS24255 (PMJ90_24255) | 5097994..5098470 | + | 477 | WP_004353334.1 | elongation factor GreAB | - |
PMJ90_RS24260 (PMJ90_24260) | 5098473..5098748 | - | 276 | WP_023088486.1 | zinc ribbon domain-containing protein | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
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Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 252 a.a. Molecular weight: 28236.34 Da Isoelectric Point: 7.7294
>T269192 WP_003086331.1 NZ_CP116722:c5094408-5093653 [Pseudomonas aeruginosa]
VSEIWRQCKGERHVRPLQGRLVRLVESQEQVATLQLVDTLEEQALLEELLESSKPPVPADAEPLHYLLKTPFRYPPLRWG
SRFGRRHEPSLFYAALKLETAMAESAYYRCVLWSGMAVPPPSGRILSEHASFEAGWKVERGIRLQAPPFSDHEAALTDIA
DYRAPQELGSAMRSAGVQAFEYRSARCPERGCNVALFTPAAFTEKRPRNLTPWLCETTAGYVAFKPAHVPGSPKIFSWEL
FLVDGKLPHPA
VSEIWRQCKGERHVRPLQGRLVRLVESQEQVATLQLVDTLEEQALLEELLESSKPPVPADAEPLHYLLKTPFRYPPLRWG
SRFGRRHEPSLFYAALKLETAMAESAYYRCVLWSGMAVPPPSGRILSEHASFEAGWKVERGIRLQAPPFSDHEAALTDIA
DYRAPQELGSAMRSAGVQAFEYRSARCPERGCNVALFTPAAFTEKRPRNLTPWLCETTAGYVAFKPAHVPGSPKIFSWEL
FLVDGKLPHPA
Download Length: 756 bp
Antitoxin
Download Length: 123 a.a. Molecular weight: 13367.63 Da Isoelectric Point: 9.9874
>AT269192 WP_003086329.1 NZ_CP116722:c5094911-5094543 [Pseudomonas aeruginosa]
MSALIKERPSADAVLAKAVLAAREQLGLTQLELAGIVGVDRSAISRWKTQGLRVDSKTGELALLLVRVYRALYALFGGQQ
EDMRHFLRTPNHHLAGEPLALMGQVQGLVHVLEYLDAIRGKV
MSALIKERPSADAVLAKAVLAAREQLGLTQLELAGIVGVDRSAISRWKTQGLRVDSKTGELALLLVRVYRALYALFGGQQ
EDMRHFLRTPNHHLAGEPLALMGQVQGLVHVLEYLDAIRGKV
Download Length: 369 bp
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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