Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) parDE/CC2985(antitoxin)
Location 132479..133026 Replicon plasmid pAtA47a_a
Accession NZ_CP116702
Organism Agrobacterium fabacearum strain A47a

Toxin (Protein)


Gene name parE Uniprot ID -
Locus tag G6M09_RS23315 Protein ID WP_153793621.1
Coordinates 132733..133026 (+) Length 98 a.a.

Antitoxin (Protein)


Gene name parD Uniprot ID F0LFW5
Locus tag G6M09_RS23310 Protein ID WP_013637268.1
Coordinates 132479..132733 (+) Length 85 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
G6M09_RS23295 (G6M09_023295) 128109..129056 + 948 WP_003519114.1 dihydrodipicolinate synthase family protein -
G6M09_RS23300 (G6M09_023300) 129284..130666 + 1383 WP_111799467.1 MFS transporter -
G6M09_RS23305 (G6M09_023305) 131207..132283 + 1077 WP_236775936.1 Fic family protein -
G6M09_RS23310 (G6M09_023310) 132479..132733 + 255 WP_013637268.1 type II toxin-antitoxin system ParD family antitoxin Antitoxin
G6M09_RS23315 (G6M09_023315) 132733..133026 + 294 WP_153793621.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
G6M09_RS23320 (G6M09_023320) 133164..134006 - 843 WP_236768996.1 hypothetical protein -
G6M09_RS23325 (G6M09_023325) 134003..135259 - 1257 WP_174073221.1 MSMEG_0569 family flavin-dependent oxidoreductase -
G6M09_RS23330 (G6M09_023330) 135271..135549 - 279 WP_013637307.1 MSMEG_0570 family nitrogen starvation response protein -
G6M09_RS23335 (G6M09_023335) 135542..136513 - 972 WP_025591200.1 sll0787 family AIR synthase-like protein -
G6M09_RS23340 (G6M09_023340) 136513..137052 - 540 WP_035201069.1 GNAT family N-acetyltransferase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..565096 565096


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(5-92)

Antitoxin

Antitoxin ParD

(6-63)


Sequences

Toxin        


Download         Length: 98 a.a.        Molecular weight: 11064.64 Da        Isoelectric Point: 5.4837

>T269139 WP_153793621.1 NZ_CP116702:132733-133026 [Agrobacterium fabacearum]
MPFSLSVQAEEDIISIAEEGIRIFGALVARQYHDELFALLELIATNPRMARESHEISPPVRIHPFKAHLVVYRVIEDGSV
FVIRIRHGHEDWAGDSF

Download         Length: 294 bp

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 9410.52 Da        Isoelectric Point: 8.5776

>AT269139 WP_013637268.1 NZ_CP116702:132479-132733 [Agrobacterium fabacearum]
MATMNVSLPDPMKDWVEAQAKTGRYSNASDYVRDLIRRDQARTDKIAEMQRFVDDGIRSGVGSRSTEELFALATSRADIS
RGRA

Download         Length: 255 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB F0LFW5

References