269137

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) pasABC/RelE-HTH
Location 318296..318758 Replicon chromosome
Accession NZ_CP116700
Organism Agrobacterium fabacearum strain A47a

Toxin (Protein)


Gene name pasB Uniprot ID A0A9E8LFT7
Locus tag G6M09_RS01500 Protein ID WP_065703878.1
Coordinates 318296..318547 (-) Length 84 a.a.

Antitoxin (Protein)


Gene name pasA Uniprot ID F0L6V5
Locus tag G6M09_RS01505 Protein ID WP_013635548.1
Coordinates 318531..318758 (-) Length 76 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
G6M09_RS01470 (G6M09_001470) 313334..314107 - 774 WP_065658316.1 L,D-transpeptidase -
G6M09_RS01475 (G6M09_001475) 314345..314974 + 630 WP_004432231.1 DNA-3-methyladenine glycosylase I -
G6M09_RS01480 (G6M09_001480) 314971..315414 + 444 WP_013635544.1 hypothetical protein -
G6M09_RS01485 (G6M09_001485) 315430..316473 - 1044 WP_065703874.1 YeiH family protein -
G6M09_RS01490 (G6M09_001490) 316556..317473 + 918 WP_004432220.1 LysR substrate-binding domain-containing protein -
G6M09_RS01495 (G6M09_001495) 317525..318289 - 765 WP_065703876.1 hypothetical protein -
G6M09_RS01500 (G6M09_001500) 318296..318547 - 252 WP_065703878.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
G6M09_RS01505 (G6M09_001505) 318531..318758 - 228 WP_013635548.1 DUF6290 family protein Antitoxin
G6M09_RS01510 (G6M09_001510) 318915..320540 + 1626 WP_065703880.1 histidine--tRNA ligase -
G6M09_RS01515 (G6M09_001515) 320545..320913 + 369 WP_026330619.1 VOC family protein -
G6M09_RS01520 (G6M09_001520) 320930..322057 + 1128 WP_004432209.1 ATP phosphoribosyltransferase regulatory subunit -
G6M09_RS01525 (G6M09_001525) 322054..322746 + 693 WP_004432208.1 ATP phosphoribosyltransferase -
G6M09_RS01530 (G6M09_001530) 322810..323256 - 447 WP_065703882.1 DoxX family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(12-82)

Antitoxin

Protein of unknown function DUF6290

(6-73)


Sequences

Toxin        


Download         Length: 84 a.a.        Molecular weight: 9851.38 Da        Isoelectric Point: 9.5687

>T269137 WP_065703878.1 NZ_CP116700:c318547-318296 [Agrobacterium fabacearum]
VIWTIEYDVLVQKEMRKIDPQTRQRIRVAALDNPRQTGAALQGSELGSFWRYRVGDYRIICDIQDHKLVVLVVEIGHRRE
IYR

Download         Length: 252 bp

Antitoxin


Download         Length: 76 a.a.        Molecular weight: 8909.92 Da        Isoelectric Point: 4.7254

>AT269137 WP_013635548.1 NZ_CP116700:c318758-318531 [Agrobacterium fabacearum]
MSKQTAIRLPDETYERLKALSERTGRTSAYYIREAIEKHIEDMEDLYLAEEATRRIQRGESKVVSAEEFWRDLDN

Download         Length: 228 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB F0L6V5

References