Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-StbC
Location 154610..155280 Replicon plasmid pAtCG920
Accession NZ_CP116698
Organism Agrobacterium fabacearum strain CG920

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag G6L96_RS24760 Protein ID WP_003517201.1
Coordinates 154861..155280 (+) Length 140 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID F0LGD9
Locus tag G6L96_RS24755 Protein ID WP_003517203.1
Coordinates 154610..154864 (+) Length 85 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
G6L96_RS24745 (G6L96_024745) 151905..152912 + 1008 WP_019565741.1 sensor histidine kinase -
G6L96_RS24750 (G6L96_024750) 153622..154227 - 606 WP_174012923.1 J domain-containing protein -
G6L96_RS24755 (G6L96_024755) 154610..154864 + 255 WP_003517203.1 plasmid stabilization protein Antitoxin
G6L96_RS24760 (G6L96_024760) 154861..155280 + 420 WP_003517201.1 type II toxin-antitoxin system VapC family toxin Toxin
G6L96_RS24765 (G6L96_024765) 155420..156316 - 897 WP_112361150.1 dihydrodipicolinate synthase family protein -
G6L96_RS24770 (G6L96_024770) 156349..157230 - 882 WP_174012793.1 SMP-30/gluconolactonase/LRE family protein -
G6L96_RS24775 (G6L96_024775) 157287..158006 - 720 WP_003517195.1 FCD domain-containing protein -
G6L96_RS24780 (G6L96_024780) 158306..160255 + 1950 WP_112361153.1 ABC transporter substrate-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Conjugative plasmid - - 1..719769 719769


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(2-126)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 140 a.a.        Molecular weight: 15036.22 Da        Isoelectric Point: 5.1532

>T269134 WP_003517201.1 NZ_CP116698:154861-155280 [Agrobacterium fabacearum]
MILLDTNVISEPWKPVPDEAVIAWLDAQAVETLFISAITIAELRFGIAAMPSGRRQTILRDRLEGEVLPHFSGRILSFDL
TTSQFYSELMARARASGKAIGTADGYIAATAAANGLTISTRDTSPFEAAGVKVINPWSR

Download         Length: 420 bp

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 9253.53 Da        Isoelectric Point: 8.9520

>AT269134 WP_003517203.1 NZ_CP116698:154610-154864 [Agrobacterium fabacearum]
MPAVTIRNLSEETHRALRVRAAHHGRSTEAEIRAIIEAAVRPPERIQLGSLLAAIGRDAELSNSDVEALQKSRDKTPAKP
MTFE

Download         Length: 255 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB F0LGD9

References