Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) parDE/CC2985(antitoxin)
Location 148879..149426 Replicon plasmid pAtLMG292a
Accession NZ_CP116690
Organism Agrobacterium tumefaciens strain LMG 292

Toxin (Protein)


Gene name parE Uniprot ID -
Locus tag G6L31_RS24170 Protein ID WP_173990325.1
Coordinates 149133..149426 (+) Length 98 a.a.

Antitoxin (Protein)


Gene name parD Uniprot ID -
Locus tag G6L31_RS24165 Protein ID WP_173990323.1
Coordinates 148879..149133 (+) Length 85 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
G6L31_RS24135 (G6L31_024135) 143909..144787 - 879 WP_173990313.1 HlyD family secretion protein -
G6L31_RS24140 (G6L31_024140) 144784..144993 - 210 WP_173990314.1 DUF1656 domain-containing protein -
G6L31_RS24145 (G6L31_024145) 144990..147020 - 2031 WP_173990316.1 FUSC family protein -
G6L31_RS24150 (G6L31_024150) 147017..147382 - 366 WP_173990318.1 hypothetical protein -
G6L31_RS24155 (G6L31_024155) 147453..148259 + 807 WP_173990320.1 helix-turn-helix transcriptional regulator -
G6L31_RS24160 (G6L31_024160) 148305..148679 + 375 WP_173990321.1 VOC family protein -
G6L31_RS24165 (G6L31_024165) 148879..149133 + 255 WP_173990323.1 type II toxin-antitoxin system ParD family antitoxin Antitoxin
G6L31_RS24170 (G6L31_024170) 149133..149426 + 294 WP_173990325.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
G6L31_RS24175 (G6L31_024175) 149783..150949 - 1167 WP_173990327.1 IS110 family transposase -
G6L31_RS24180 (G6L31_024180) 151066..152019 - 954 WP_173990329.1 LysR substrate-binding domain-containing protein -
G6L31_RS24185 (G6L31_024185) 152113..153072 + 960 WP_173990331.1 MBL fold metallo-hydrolase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..205192 205192


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(5-92)

Antitoxin

Antitoxin ParD

(6-64)


Sequences

Toxin        


Download         Length: 98 a.a.        Molecular weight: 11115.82 Da        Isoelectric Point: 6.2160

>T269129 WP_173990325.1 NZ_CP116690:149133-149426 [Agrobacterium tumefaciens]
MLFSLSVQAEEDIVSIAEEGIRIFGALVAKRYHDELLALLEIIATNPRMARERHEISPPVRIHPFKAHLVVYRIVEDGSI
FVIRIRHGHEDWAGDSF

Download         Length: 294 bp

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 9456.56 Da        Isoelectric Point: 6.3323

>AT269129 WP_173990323.1 NZ_CP116690:148879-149133 [Agrobacterium tumefaciens]
MATMNVSLPDPMKDWVEAQAKTGRYSNASDYVRDLIRRDQARTDKIAEMQRFVDDGIRSGVGSRSMDELFAEATARSEIS
RGRA

Download         Length: 255 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References