Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-VapB
Location 2017306..2017886 Replicon chromosome
Accession NZ_CP116689
Organism Agrobacterium tumefaciens strain LMG 292

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag G6L31_RS22655 Protein ID WP_080827689.1
Coordinates 2017306..2017689 (-) Length 128 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag G6L31_RS22660 Protein ID WP_173988395.1
Coordinates 2017686..2017886 (-) Length 67 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
G6L31_RS22640 (G6L31_022640) 2013507..2014385 - 879 WP_173988398.1 LysR substrate-binding domain-containing protein -
G6L31_RS22645 (G6L31_022645) 2014520..2015677 + 1158 WP_173988397.1 class C beta-lactamase -
G6L31_RS22650 (G6L31_022650) 2015935..2017257 + 1323 WP_173988396.1 solute carrier family 23 protein -
G6L31_RS22655 (G6L31_022655) 2017306..2017689 - 384 WP_080827689.1 type II toxin-antitoxin system VapC family toxin Toxin
G6L31_RS22660 (G6L31_022660) 2017686..2017886 - 201 WP_173988395.1 type II toxin-antitoxin system VapB family antitoxin Antitoxin
G6L31_RS22665 (G6L31_022665) 2017998..2018630 - 633 WP_173988394.1 TetR/AcrR family transcriptional regulator -
G6L31_RS22670 (G6L31_022670) 2018719..2019492 + 774 WP_173988393.1 SDR family oxidoreductase -
G6L31_RS22675 (G6L31_022675) 2019749..2020234 - 486 WP_173988392.1 cupin domain-containing protein -
G6L31_RS22680 (G6L31_022680) 2020325..2021566 - 1242 WP_173988390.1 Zn-dependent hydrolase -
G6L31_RS22685 (G6L31_022685) 2021580..2022422 - 843 WP_173988388.1 BtpA/SgcQ family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(2-111)

Antitoxin

Bacterial antitoxin of type II TA system, VapB

(1-42)


Sequences

Toxin        


Download         Length: 128 a.a.        Molecular weight: 14382.52 Da        Isoelectric Point: 6.7552

>T269128 WP_080827689.1 NZ_CP116689:c2017689-2017306 [Agrobacterium tumefaciens]
VILVDTSVWIDHFRQRNVELREIIENDRLLCHPFIIGELALGSLRDREAVIGFLQAQRETVVATHDEVMTFIDRYSIFSM
GIGYTDAHLLASTLLDRRVSLWTRDKRLLAAAQKAGASVHMAASNPH

Download         Length: 384 bp

Antitoxin


Download         Length: 67 a.a.        Molecular weight: 7238.37 Da        Isoelectric Point: 10.9054

>AT269128 WP_173988395.1 NZ_CP116689:c2017886-2017686 [Agrobacterium tumefaciens]
MRSTINLDDKLMERAKSLTGTKETAALVRQALETLVRVESGKRLIALGGSMPEAEAAPRRRSDVNK

Download         Length: 201 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References