Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PumAB/upstrm_HI1419-dnstrm_HI1420
Location 2098016..2098616 Replicon chromosome
Accession NZ_CP116688
Organism Agrobacterium tumefaciens strain LMG 292

Toxin (Protein)


Gene name PumA Uniprot ID -
Locus tag G6L31_RS10380 Protein ID WP_173987675.1
Coordinates 2098016..2098303 (+) Length 96 a.a.

Antitoxin (Protein)


Gene name PumB Uniprot ID -
Locus tag G6L31_RS10385 Protein ID WP_080824403.1
Coordinates 2098311..2098616 (+) Length 102 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
G6L31_RS10355 (G6L31_010355) 2093830..2094723 - 894 WP_173987562.1 hemin ABC transporter substrate-binding protein -
G6L31_RS10360 (G6L31_010360) 2094910..2095257 + 348 WP_006314959.1 antibiotic biosynthesis monooxygenase -
G6L31_RS10365 (G6L31_010365) 2095268..2095792 + 525 WP_080827222.1 heme utilization cystosolic carrier protein HutX -
G6L31_RS10370 (G6L31_010370) 2096080..2096856 + 777 WP_173987563.1 YbaY family lipoprotein -
G6L31_RS10375 (G6L31_010375) 2097078..2097962 + 885 WP_173987564.1 formyltetrahydrofolate deformylase -
G6L31_RS10380 (G6L31_010380) 2098016..2098303 + 288 WP_173987675.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
G6L31_RS10385 (G6L31_010385) 2098311..2098616 + 306 WP_080824403.1 putative addiction module antidote protein Antitoxin
G6L31_RS10390 (G6L31_010390) 2098629..2100023 - 1395 WP_173987565.1 sensor histidine kinase -
G6L31_RS10395 (G6L31_010395) 2100020..2100700 - 681 WP_010972345.1 response regulator transcription factor -
G6L31_RS10400 (G6L31_010400) 2100771..2101850 + 1080 WP_173987677.1 ABC transporter substrate-binding protein -
G6L31_RS10405 (G6L31_010405) 2102105..2103049 + 945 WP_020809150.1 tripartite tricarboxylate transporter substrate binding protein -
G6L31_RS10410 (G6L31_010410) 2103046..2103540 + 495 WP_173987566.1 tripartite tricarboxylate transporter TctB family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-like

(9-88)

Antitoxin

Uncharacterized protein HI1420

(4-96)


Sequences

Toxin        


Download         Length: 96 a.a.        Molecular weight: 10613.18 Da        Isoelectric Point: 10.3359

>T269127 WP_173987675.1 NZ_CP116688:2098016-2098303 [Agrobacterium tumefaciens]
IRETNEFADWLAGLRDVQARARIARRIYRLADGNPGDVKPVGEGVSELRIDLGPGYRVYFVRQGDVVIILLCGGDKSSQS
RDIAKARRMARALKE

Download         Length: 288 bp

Antitoxin


Download         Length: 102 a.a.        Molecular weight: 10498.78 Da        Isoelectric Point: 4.5720

>AT269127 WP_080824403.1 NZ_CP116688:2098311-2098616 [Agrobacterium tumefaciens]
MPLATRDYDAARYLDSDEALAAYIADATESGDAQELAHALGVVARAKGMTDLSRQTGLPRQTLYKALSGEGNPELATIAK
VADALGYKLSLVAKSAAETAA

Download         Length: 306 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References