Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) pasABC/RelE-HTH
Location 330969..331449 Replicon chromosome
Accession NZ_CP116688
Organism Agrobacterium tumefaciens strain LMG 292

Toxin (Protein)


Gene name pasB Uniprot ID -
Locus tag G6L31_RS01605 Protein ID WP_173986348.1
Coordinates 330969..331238 (-) Length 90 a.a.

Antitoxin (Protein)


Gene name pasA Uniprot ID A0A176XG90
Locus tag G6L31_RS01610 Protein ID WP_063947698.1
Coordinates 331222..331449 (-) Length 76 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
G6L31_RS01575 (G6L31_001575) 326025..326804 - 780 WP_173986343.1 L,D-transpeptidase -
G6L31_RS01580 (G6L31_001580) 327042..327671 + 630 WP_173986344.1 DNA-3-methyladenine glycosylase I -
G6L31_RS01585 (G6L31_001585) 327668..328111 + 444 WP_173986345.1 hypothetical protein -
G6L31_RS01590 (G6L31_001590) 328122..329165 - 1044 WP_173986346.1 YeiH family protein -
G6L31_RS01595 (G6L31_001595) 329247..330164 + 918 WP_080855993.1 LysR family transcriptional regulator -
G6L31_RS01600 (G6L31_001600) 330198..330962 - 765 WP_173986347.1 hypothetical protein -
G6L31_RS01605 (G6L31_001605) 330969..331238 - 270 WP_173986348.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
G6L31_RS01610 (G6L31_001610) 331222..331449 - 228 WP_063947698.1 DUF6290 family protein Antitoxin
G6L31_RS01615 (G6L31_001615) 331606..333147 + 1542 WP_173986349.1 histidine--tRNA ligase -
G6L31_RS01620 (G6L31_001620) 333316..334443 + 1128 WP_080825891.1 ATP phosphoribosyltransferase regulatory subunit -
G6L31_RS01625 (G6L31_001625) 334440..335132 + 693 WP_080825889.1 ATP phosphoribosyltransferase -
G6L31_RS01630 (G6L31_001630) 335191..335637 - 447 WP_080825888.1 DoxX family protein -
G6L31_RS01635 (G6L31_001635) 335793..336227 - 435 WP_080825887.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(5-88)

Antitoxin

Protein of unknown function DUF6290

(6-73)


Sequences

Toxin        


Download         Length: 90 a.a.        Molecular weight: 10729.39 Da        Isoelectric Point: 9.8259

>T269124 WP_173986348.1 NZ_CP116688:c331238-330969 [Agrobacterium tumefaciens]
VIWTIEYHTLVQKEMRKINPEVRRRIRSFLHERLAALDDPRQTGAALQGSELGNYWRYRVGDYRIICDIQDHKLVVLVVE
IGHRREIYR

Download         Length: 270 bp

Antitoxin


Download         Length: 76 a.a.        Molecular weight: 8923.95 Da        Isoelectric Point: 4.7254

>AT269124 WP_063947698.1 NZ_CP116688:c331449-331222 [Agrobacterium tumefaciens]
MSKQTAIRLPDETYERLKALSERTGRTSAYYIREAIEKHIEDMEDLYLAEEATRRIQRGESKVISAEEFWRDLDN

Download         Length: 228 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB A0A176XG90

References