Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) /BrnT(toxin)
Location 1994067..1994559 Replicon chromosome
Accession NZ_CP116683
Organism Agrobacterium fabrum strain 2788

Toxin (Protein)


Gene name - Uniprot ID -
Locus tag G6L39_RS09895 Protein ID WP_080807612.1
Coordinates 1994290..1994559 (-) Length 90 a.a.

Antitoxin (Protein)


Gene name - Uniprot ID -
Locus tag G6L39_RS09890 Protein ID WP_080807616.1
Coordinates 1994067..1994309 (-) Length 81 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
G6L39_RS09870 (G6L39_009870) 1989317..1990309 + 993 WP_080811835.1 glutathione S-transferase family protein -
G6L39_RS09875 (G6L39_009875) 1990327..1990818 - 492 WP_010972183.1 NUDIX domain-containing protein -
G6L39_RS09880 (G6L39_009880) 1990885..1991835 + 951 WP_080807622.1 metallophosphoesterase -
G6L39_RS09885 (G6L39_009885) 1992040..1993749 - 1710 WP_080807619.1 2-isopropylmalate synthase -
G6L39_RS09890 (G6L39_009890) 1994067..1994309 - 243 WP_080807616.1 CopG family antitoxin Antitoxin
G6L39_RS09895 (G6L39_009895) 1994290..1994559 - 270 WP_080807612.1 BrnT family toxin Toxin
G6L39_RS09900 (G6L39_009900) 1994594..1995772 - 1179 WP_080807609.1 benzoate/H(+) symporter BenE family transporter -
G6L39_RS09905 (G6L39_009905) 1996035..1997117 + 1083 WP_173992753.1 esterase-like activity of phytase family protein -
G6L39_RS09910 (G6L39_009910) 1997190..1997834 - 645 WP_080807603.1 NrsF family protein -
G6L39_RS09915 (G6L39_009915) 1997831..1998379 - 549 WP_080728775.1 sigma-70 family RNA polymerase sigma factor -
G6L39_RS09920 (G6L39_009920) 1998565..1998822 + 258 WP_080807599.1 pentapeptide MXKDX repeat protein -
G6L39_RS09925 (G6L39_009925) 1998929..1999510 - 582 WP_006314627.1 ATP-dependent Clp protease proteolytic subunit -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Ribonuclease toxin, BrnT, of type II toxin-antitoxin system

(5-80)

Antitoxin

CopG antitoxin

(7-71)


Sequences

Toxin        


Download         Length: 90 a.a.        Molecular weight: 10820.24 Da        Isoelectric Point: 8.0187

>T269121 WP_080807612.1 NZ_CP116683:c1994559-1994290 [Agrobacterium fabrum]
MDFEFDPAKSESNKDKHGIDFVEARGLWLDEKRLVVPLETTLEERYIMIAQLRGKCWSAVYTYRHDRVRIISVRRSRDKE
KQRYEDDQR

Download         Length: 270 bp

Antitoxin


Download         Length: 81 a.a.        Molecular weight: 9110.32 Da        Isoelectric Point: 4.5626

>AT269121 WP_080807616.1 NZ_CP116683:c1994309-1994067 [Agrobacterium fabrum]
MKTISAEEFDRKFDEGEDIDDYLDWSKASRPGLEMVHVDVDLPEKVLRRVDAEAARLGMTRQSLMAKWIAESLEAGRVGK

Download         Length: 243 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References