269119

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) pasABC/RelE-HTH
Location 338254..338740 Replicon chromosome
Accession NZ_CP116683
Organism Agrobacterium fabrum strain 2788

Toxin (Protein)


Gene name pasB Uniprot ID -
Locus tag G6L39_RS01615 Protein ID WP_080812136.1
Coordinates 338254..338523 (-) Length 90 a.a.

Antitoxin (Protein)


Gene name pasA Uniprot ID A0A7Z7BLB4
Locus tag G6L39_RS01620 Protein ID WP_006313156.1
Coordinates 338507..338740 (-) Length 78 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
G6L39_RS01585 (G6L39_001585) 333305..334081 - 777 WP_006313140.1 L,D-transpeptidase -
G6L39_RS01590 (G6L39_001590) 334320..334949 + 630 WP_006313142.1 DNA-3-methyladenine glycosylase I -
G6L39_RS01595 (G6L39_001595) 334946..335389 + 444 WP_006313144.1 hypothetical protein -
G6L39_RS01600 (G6L39_001600) 335415..336458 - 1044 WP_035256280.1 YeiH family protein -
G6L39_RS01605 (G6L39_001605) 336540..337457 + 918 WP_010971057.1 LysR family transcriptional regulator -
G6L39_RS01610 (G6L39_001610) 337483..338247 - 765 WP_080810439.1 hypothetical protein -
G6L39_RS01615 (G6L39_001615) 338254..338523 - 270 WP_080812136.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
G6L39_RS01620 (G6L39_001620) 338507..338740 - 234 WP_006313156.1 DUF6290 family protein Antitoxin
G6L39_RS01625 (G6L39_001625) 338897..340420 + 1524 WP_080810435.1 histidine--tRNA ligase -
G6L39_RS01630 (G6L39_001630) 340425..340793 + 369 WP_080810433.1 VOC family protein -
G6L39_RS01635 (G6L39_001635) 340810..341937 + 1128 WP_080810430.1 ATP phosphoribosyltransferase regulatory subunit -
G6L39_RS01640 (G6L39_001640) 341934..342626 + 693 WP_080810428.1 ATP phosphoribosyltransferase -
G6L39_RS01645 (G6L39_001645) 342691..343137 - 447 WP_006313161.1 DoxX family protein -
G6L39_RS01650 (G6L39_001650) 343293..343712 - 420 WP_230060738.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(5-88)

Antitoxin

Protein of unknown function DUF6290

(6-73)


Sequences

Toxin        


Download         Length: 90 a.a.        Molecular weight: 10436.96 Da        Isoelectric Point: 10.0416

>T269119 WP_080812136.1 NZ_CP116683:c338523-338254 [Agrobacterium fabrum]
MIWRIEFQRNAVKQLGKLTKSDANRIVSFLTDRVAQDDNPRRAGAALQGSELGNFWHYRVGDYRIICDIQDHKLVVLVVE
IGHRREIYR

Download         Length: 270 bp

Antitoxin


Download         Length: 78 a.a.        Molecular weight: 9223.39 Da        Isoelectric Point: 4.7543

>AT269119 WP_006313156.1 NZ_CP116683:c338740-338507 [Agrobacterium fabrum]
MSKQTAIRLPDETYERLKALSERTGRTSAYYIREAIEKHIEDMEDLYLAEEAMRKHIANKERTYTLEEVMRDLDLEN

Download         Length: 234 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB A0A7Z7BLB4

References