Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/-
Location 471163..471816 Replicon chromosome
Accession NZ_CP116680
Organism Acinetobacter baumannii Canada BC-5

Toxin (Protein)


Gene name cptA Uniprot ID B0V6V2
Locus tag POF49_RS02275 Protein ID WP_000931890.1
Coordinates 471427..471816 (+) Length 130 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID V5V966
Locus tag POF49_RS02270 Protein ID WP_001288210.1
Coordinates 471163..471420 (+) Length 86 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
POF49_RS02250 (POF49_02250) 466679..467686 + 1008 WP_000198631.1 DNA-directed RNA polymerase subunit alpha -
POF49_RS02255 (POF49_02255) 467705..468082 + 378 WP_001216378.1 50S ribosomal protein L17 -
POF49_RS02260 (POF49_02260) 468263..469753 + 1491 WP_000415133.1 NAD(P)/FAD-dependent oxidoreductase -
POF49_RS02265 (POF49_02265) 469803..470975 - 1173 WP_001190546.1 acyl-CoA dehydrogenase family protein -
POF49_RS02270 (POF49_02270) 471163..471420 + 258 WP_001288210.1 succinate dehydrogenase assembly factor 2 Antitoxin
POF49_RS02275 (POF49_02275) 471427..471816 + 390 WP_000931890.1 membrane protein Toxin
POF49_RS02280 (POF49_02280) 472586..473671 + 1086 WP_000049106.1 hypothetical protein -
POF49_RS02285 (POF49_02285) 473749..474315 + 567 WP_000651536.1 rhombosortase -
POF49_RS02290 (POF49_02290) 474503..476698 + 2196 WP_001158905.1 TRAP transporter large permease subunit -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Flavinator of succinate dehydrogenase

(10-82)


Sequences

Toxin        


Download         Length: 130 a.a.        Molecular weight: 15649.98 Da        Isoelectric Point: 10.4623

>T269109 WP_000931890.1 NZ_CP116680:471427-471816 [Acinetobacter baumannii Canada BC-5]
MLNHLNFKLKYSRFSIIFQFFIGLSLAILFYQLMPLLWWLVVISLLFISFIFFLKRPQLAKIAYLDKKLWSLAYHSQNTI
SRVKILKIIDYQIFIVIYFEGHKTLTSIIWFDQMSLAEWKKLKTLEKLY

Download         Length: 390 bp

Antitoxin


Download         Length: 86 a.a.        Molecular weight: 10318.77 Da        Isoelectric Point: 4.6150

>AT269109 WP_001288210.1 NZ_CP116680:471163-471420 [Acinetobacter baumannii Canada BC-5]
MSEEMTLEERKVIYRARRGLKEIDVYFDPYVKNYYLKADPAEKALFAELVEQEDPDLLDWFMEVSEPPRTELRDFIYKLK
HYVHG

Download         Length: 258 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A0J1A4U0

Antitoxin

Source ID Structure
AlphaFold DB A0A7U4BQM7

References