Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-VagC
Location 48796..49421 Replicon plasmid pEtSC002-3
Accession NZ_CP116678
Organism Edwardsiella tarda strain SC002

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag PHA77_RS18505 Protein ID WP_279509900.1
Coordinates 49023..49421 (+) Length 133 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag PHA77_RS18500 Protein ID WP_279509898.1
Coordinates 48796..49023 (+) Length 76 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PHA77_RS18500 (PHA77_18500) 48796..49023 + 228 WP_279509898.1 toxin-antitoxin system antitoxin VapB Antitoxin
PHA77_RS18505 (PHA77_18505) 49023..49421 + 399 WP_279509900.1 tRNA(fMet)-specific endonuclease VapC Toxin
PHA77_RS18510 (PHA77_18510) 49499..51703 - 2205 WP_279509902.1 type IV conjugative transfer system coupling protein TraD -
PHA77_RS18515 (PHA77_18515) 51790..52287 - 498 WP_279509904.1 conjugal transfer protein TraS -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..154848 154848


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(4-125)

Antitoxin

SpoVT-AbrB domain

(7-52)


Sequences

Toxin        


Download         Length: 133 a.a.        Molecular weight: 14831.13 Da        Isoelectric Point: 8.5070

>T269107 WP_279509900.1 NZ_CP116678:49023-49421 [Edwardsiella tarda]
MLKYMLDTNICIFTLKNRPAQVREKFNLHHNQMCISAITLMELIYGAEKSQAPERNLAVIEGVIARLTVLNYDVPAAAHS
GQLRAEQARQGQPIGPYDQMIAGHARSQGLILVTNNTREFARVSGLRIEDWV

Download         Length: 399 bp

Antitoxin


Download         Length: 76 a.a.        Molecular weight: 8397.40 Da        Isoelectric Point: 4.4013

>AT269107 WP_279509898.1 NZ_CP116678:48796-49023 [Edwardsiella tarda]
METTVFLSNRSQAVRLPKAVALPGDVKRVDVVAVGRTRIITPAGESWDSWFEGESVSADFMASREQPLEQEREDF

Download         Length: 228 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References