Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-VagC
Location 48796..49421 Replicon plasmid pEtSC002-3
Accession NZ_CP116678
Organism Edwardsiella tarda strain SC002

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag PHA77_RS18505 Protein ID WP_279509900.1
Coordinates 49023..49421 (+) Length 133 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag PHA77_RS18500 Protein ID WP_279509898.1
Coordinates 48796..49023 (+) Length 76 a.a.

Genomic Context

PHA77_RS18500PHA77_RS18505PHA77_RS18510PHA77_RS18515
Location: 48796..49023 (228 bp)
Type: Antitoxin
Protein ID: WP_279509898.1
Location: 49023..49421 (399 bp)
Type: Toxin
Protein ID: WP_279509900.1
Location: 49499..51703 (2205 bp)
Type: Others
Protein ID: WP_279509902.1
Location: 51790..52287 (498 bp)
Type: Others
Protein ID: WP_279509904.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
PHA77_RS18500 (PHA77_18500)48796..49023+228WP_279509898.1toxin-antitoxin system antitoxin VapBAntitoxin
PHA77_RS18505 (PHA77_18505)49023..49421+399WP_279509900.1tRNA(fMet)-specific endonuclease VapCToxin
PHA77_RS18510 (PHA77_18510)49499..51703-2205WP_279509902.1type IV conjugative transfer system coupling protein TraD-
PHA77_RS18515 (PHA77_18515)51790..52287-498WP_279509904.1conjugal transfer protein TraS-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
-insideNon-Mobilizable plasmid--1..154848154848


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(4-125)

Antitoxin

SpoVT-AbrB domain

(7-52)


Sequences

Toxin        


Download         Length: 133 a.a.        Molecular weight: 14831.13 Da        Isoelectric Point: 8.5070

>T269107 WP_279509900.1 NZ_CP116678:49023-49421 [Edwardsiella tarda]
MLKYMLDTNICIFTLKNRPAQVREKFNLHHNQMCISAITLMELIYGAEKSQAPERNLAVIEGVIARLTVLNYDVPAAAHS
GQLRAEQARQGQPIGPYDQMIAGHARSQGLILVTNNTREFARVSGLRIEDWV

Download         Length: 399 bp

Antitoxin


Download         Length: 76 a.a.        Molecular weight: 8397.40 Da        Isoelectric Point: 4.4013

>AT269107 WP_279509898.1 NZ_CP116678:48796-49023 [Edwardsiella tarda]
METTVFLSNRSQAVRLPKAVALPGDVKRVDVVAVGRTRIITPAGESWDSWFEGESVSADFMASREQPLEQEREDF

Download         Length: 228 bp


Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
No matching records found

Antitoxin

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Source
ID
Structure
No matching records found

References