Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) ccdAB/CcdA(antitoxin)
Location 41337..41890 Replicon plasmid pEtSC002-3
Accession NZ_CP116678
Organism Edwardsiella tarda strain SC002

Toxin (Protein)


Gene name ccdB Uniprot ID -
Locus tag PHA77_RS18475 Protein ID WP_279509893.1
Coordinates 41337..41651 (-) Length 105 a.a.

Antitoxin (Protein)


Gene name ccdA Uniprot ID -
Locus tag PHA77_RS18480 Protein ID WP_279509894.1
Coordinates 41654..41890 (-) Length 79 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PHA77_RS18455 (PHA77_18455) 36425..36649 - 225 Protein_43 IS66 family insertion sequence element accessory protein TnpB -
PHA77_RS18460 (PHA77_18460) 37035..37982 - 948 WP_279509889.1 Rpn family recombination-promoting nuclease/putative transposase -
PHA77_RS18465 (PHA77_18465) 38944..39861 - 918 WP_279509971.1 Replication protein -
PHA77_RS18470 (PHA77_18470) 40593..41024 - 432 WP_279509892.1 hypothetical protein -
PHA77_RS18475 (PHA77_18475) 41337..41651 - 315 WP_279509893.1 CcdB family protein Toxin
PHA77_RS18480 (PHA77_18480) 41654..41890 - 237 WP_279509894.1 type II toxin-antitoxin system CcdA family antitoxin Antitoxin
PHA77_RS18485 (PHA77_18485) 42002..42622 - 621 WP_279509895.1 fertility inhibition protein FinO -
PHA77_RS18490 (PHA77_18490) 42636..43361 - 726 WP_141112577.1 type-F conjugative transfer system pilin acetylase TraX -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..154848 154848


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin CcdB

(2-103)

Antitoxin

Post-segregation antitoxin CcdA

(9-78)


Sequences

Toxin        


Download         Length: 105 a.a.        Molecular weight: 11620.64 Da        Isoelectric Point: 7.9859

>T269106 WP_279509893.1 NZ_CP116678:c41651-41337 [Edwardsiella tarda]
MQFTVYRNIGKSAVYPLLLDVTSDIIGQLNRRIVIPLLPIEKYPGSARPERLVPLVRLTDDKEYAVMTHEMASIPARSLG
GVFCDASLYRTQIKAAIDFLLDGI

Download         Length: 315 bp

Antitoxin


Download         Length: 79 a.a.        Molecular weight: 8952.02 Da        Isoelectric Point: 6.4610

>AT269106 WP_279509894.1 NZ_CP116678:c41890-41654 [Edwardsiella tarda]
MTTVQRATQSVTMTVERVLLSRARKAGINLSATLTAALDAELRQYEAKKWKEENSEALESLNRFHDEHGCFSDEYRTF

Download         Length: 237 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References