Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | DhiAT/dnstrm_HI1420(antitoxin) |
| Location | 1957703..1958482 | Replicon | chromosome |
| Accession | NZ_CP116675 | ||
| Organism | Edwardsiella tarda strain SC002 | ||
Toxin (Protein)
| Gene name | dhiT | Uniprot ID | - |
| Locus tag | PHA77_RS09095 | Protein ID | WP_198077053.1 |
| Coordinates | 1957703..1957960 (+) | Length | 86 a.a. |
Antitoxin (Protein)
| Gene name | dhiA | Uniprot ID | - |
| Locus tag | PHA77_RS09100 | Protein ID | WP_279508115.1 |
| Coordinates | 1957970..1958482 (+) | Length | 171 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| PHA77_RS09065 (PHA77_09065) | 1953095..1953877 | - | 783 | WP_279508099.1 | antA/AntB antirepressor family protein | - |
| PHA77_RS09070 (PHA77_09070) | 1954058..1954609 | - | 552 | WP_279508101.1 | putative peptidoglycan-binding domain-containing protein | - |
| PHA77_RS09075 (PHA77_09075) | 1954612..1954959 | - | 348 | WP_109579041.1 | phage holin, lambda family | - |
| PHA77_RS09080 (PHA77_09080) | 1955129..1955947 | - | 819 | WP_279508106.1 | hypothetical protein | - |
| PHA77_RS09085 (PHA77_09085) | 1956022..1956327 | - | 306 | WP_279508108.1 | hypothetical protein | - |
| PHA77_RS09090 (PHA77_09090) | 1956560..1957321 | - | 762 | WP_279508109.1 | antA/AntB antirepressor family protein | - |
| PHA77_RS09095 (PHA77_09095) | 1957703..1957960 | + | 258 | WP_198077053.1 | DUF4160 domain-containing protein | Toxin |
| PHA77_RS09100 (PHA77_09100) | 1957970..1958482 | + | 513 | WP_279508115.1 | DUF2442 domain-containing protein | Antitoxin |
| PHA77_RS09105 (PHA77_09105) | 1958853..1959356 | + | 504 | WP_279508117.1 | hypothetical protein | - |
| PHA77_RS09110 (PHA77_09110) | 1959417..1959719 | - | 303 | WP_279508119.1 | DUF1364 family protein | - |
| PHA77_RS09115 (PHA77_09115) | 1959722..1960366 | - | 645 | WP_279508120.1 | DUF1367 family protein | - |
| PHA77_RS09120 (PHA77_09120) | 1960476..1960823 | - | 348 | WP_098143178.1 | hypothetical protein | - |
| PHA77_RS09125 (PHA77_09125) | 1960851..1962233 | - | 1383 | WP_279508126.1 | DnaB-like helicase C-terminal domain-containing protein | - |
| PHA77_RS09130 (PHA77_09130) | 1962230..1963168 | - | 939 | WP_279508128.1 | helix-turn-helix domain-containing protein | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| - | inside | Prophage | - | - | 1921259..1990509 | 69250 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 86 a.a. Molecular weight: 9625.29 Da Isoelectric Point: 7.4665
>T269103 WP_198077053.1 NZ_CP116675:1957703-1957960 [Edwardsiella tarda]
MPEIDALMGLSFVMYFFDNQTHSLPHVHVKYGEFELVIGIDSGEALEGYLPPKKRKLAESHIKANKTRLLAMWQMAVNGM
HPGKL
MPEIDALMGLSFVMYFFDNQTHSLPHVHVKYGEFELVIGIDSGEALEGYLPPKKRKLAESHIKANKTRLLAMWQMAVNGM
HPGKL
Download Length: 258 bp
Antitoxin
Download Length: 171 a.a. Molecular weight: 18175.57 Da Isoelectric Point: 8.5800
>AT269103 WP_279508115.1 NZ_CP116675:1957970-1958482 [Edwardsiella tarda]
MLKIIDVDVVGAHVIEVEFSDGFRGRADLAALFSKPPFSAIADFNRFSLTASGVLNWGDAELSADTVRRMSKGAVVSASS
RSLTPENVEAILRQATWESMSEGRPDILQAALRGYAEQLGHADVIKRAGIASRSSAYKTLSPSTNPSFKSLAKISGAILA
IVRENNTQHG
MLKIIDVDVVGAHVIEVEFSDGFRGRADLAALFSKPPFSAIADFNRFSLTASGVLNWGDAELSADTVRRMSKGAVVSASS
RSLTPENVEAILRQATWESMSEGRPDILQAALRGYAEQLGHADVIKRAGIASRSSAYKTLSPSTNPSFKSLAKISGAILA
IVRENNTQHG
Download Length: 513 bp
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
Structures
Toxin
| Source | ID | Structure |
|---|
Antitoxin
| Source | ID | Structure |
|---|