Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) EcnAB/-
Location 4769916..4770281 Replicon chromosome
Accession NZ_CP116672
Organism Xanthomonas hortorum pv. pelargonii strain 305

Toxin (Protein)


Gene name EcnB Uniprot ID V7Z935
Locus tag PML25_RS20145 Protein ID WP_006451341.1
Coordinates 4769916..4770050 (-) Length 45 a.a.

Antitoxin (Protein)


Gene name EcnA Uniprot ID V7Z8F2
Locus tag PML25_RS20150 Protein ID WP_006451340.1
Coordinates 4770129..4770281 (-) Length 51 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PML25_RS20130 (PML25_20130) 4766856..4767842 - 987 WP_233366624.1 MBL fold metallo-hydrolase -
PML25_RS20135 (PML25_20135) 4768001..4769290 - 1290 WP_168959806.1 tryptophan--tRNA ligase -
PML25_RS20140 (PML25_20140) 4769464..4769673 - 210 WP_006451342.1 CsbD family protein -
PML25_RS20145 (PML25_20145) 4769916..4770050 - 135 WP_006451341.1 entericidin A/B family lipoprotein Toxin
PML25_RS20150 (PML25_20150) 4770129..4770281 - 153 WP_006451340.1 entericidin A/B family lipoprotein Antitoxin
PML25_RS20155 (PML25_20155) 4770391..4771314 - 924 WP_046931980.1 arginase -
PML25_RS20160 (PML25_20160) 4771777..4772229 + 453 WP_006452080.1 roadblock/LC7 domain-containing protein -
PML25_RS20165 (PML25_20165) 4772293..4772652 + 360 WP_006452081.1 hypothetical protein -
PML25_RS20170 (PML25_20170) 4772746..4773663 + 918 WP_168959807.1 hypothetical protein -
PML25_RS20175 (PML25_20175) 4773660..4774202 + 543 WP_006452083.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Entericidin A/B

(23-42)

Antitoxin

Entericidin A/B

(23-42)


Sequences

Toxin        


Download         Length: 45 a.a.        Molecular weight: 4493.34 Da        Isoelectric Point: 9.3487

>T269095 WP_006451341.1 NZ_CP116672:c4770050-4769916 [Xanthomonas hortorum pv. pelargonii]
MKRAIMLLVLSVFSVGMLAGCNTVAGAGKDVQGAGEKVEDAARK

Download         Length: 135 bp

Antitoxin


Download         Length: 51 a.a.        Molecular weight: 5168.11 Da        Isoelectric Point: 8.2782

>AT269095 WP_006451340.1 NZ_CP116672:c4770281-4770129 [Xanthomonas hortorum pv. pelargonii]
MKRLLTLMVLGLFSAGVMTGCNTMAGAGKDMQGAGEKVEKKADNCSDGKC

Download         Length: 153 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A6V7EZD1

Antitoxin

Source ID Structure
AlphaFold DB A0A2N7V051

References