269094

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PP_4151-4152/excise(antitoxin)
Location 4365532..4366571 Replicon chromosome
Accession NZ_CP116672
Organism Xanthomonas hortorum pv. pelargonii strain 305

Toxin (Protein)


Gene name PP_4152 Uniprot ID -
Locus tag PML25_RS18315 Protein ID WP_233366293.1
Coordinates 4365532..4366035 (-) Length 168 a.a.

Antitoxin (Protein)


Gene name PP_4151 Uniprot ID -
Locus tag PML25_RS18320 Protein ID WP_168957174.1
Coordinates 4366104..4366571 (-) Length 156 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PML25_RS18300 (PML25_18300) 4361523..4364156 - 2634 WP_233366295.1 TonB-dependent receptor -
PML25_RS18305 (PML25_18305) 4364422..4364775 + 354 WP_043888904.1 6-carboxytetrahydropterin synthase QueD -
PML25_RS18310 (PML25_18310) 4364969..4365331 + 363 WP_006450461.1 phasin family protein -
PML25_RS18315 (PML25_18315) 4365532..4366035 - 504 WP_233366293.1 PIN domain-containing protein Toxin
PML25_RS18320 (PML25_18320) 4366104..4366571 - 468 WP_168957174.1 helix-turn-helix domain-containing protein Antitoxin
PML25_RS18325 (PML25_18325) 4366710..4367384 - 675 WP_168957175.1 dethiobiotin synthase -
PML25_RS18330 (PML25_18330) 4367503..4367985 + 483 WP_168957176.1 GAF domain-containing protein -
PML25_RS18335 (PML25_18335) 4367982..4368374 + 393 WP_168957177.1 TfoX/Sxy family protein -
PML25_RS18340 (PML25_18340) 4368487..4369437 - 951 WP_168957178.1 alpha/beta hydrolase-fold protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(6-91)

Antitoxin

SinI-like, DNA-binding domain

(84-130)


Sequences

Toxin        


Download         Length: 168 a.a.        Molecular weight: 18783.57 Da        Isoelectric Point: 6.4861

>T269094 WP_233366293.1 NZ_CP116672:c4366035-4365532 [Xanthomonas hortorum pv. pelargonii]
MWLGLSGRFRARWSVQIHQEWKRNLLLNRRDLTAEQVDRTSALMDRAIPDALVTGHEPLIAGLQLPDADDRHVLAAAIRC
SASVIVTFNLKDFPSATLAPFGIEAQHPDEFIENLFDLDQAAVVSAAQRQRAQLTNPGMEVERYLEVLLRQGLVQTVKAL
TIYRTVL

Download         Length: 504 bp

Antitoxin


Download         Length: 156 a.a.        Molecular weight: 17375.85 Da        Isoelectric Point: 5.9974

>AT269094 WP_168957174.1 NZ_CP116672:c4366571-4366104 [Xanthomonas hortorum pv. pelargonii]
MSNIAPSKMVLPVEREVAAAVQGQRALAAYLATSFETQRIQIFDDQNQAHQVELPTSALRLLMDILAELADGNAVQVVPI
HAELTTQEAADLLNVSRPHMVKLMEEGALAFHRTGRHRRVRFADLMQFKRERERASEQAMQELATQAQELALGYQ

Download         Length: 468 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References