Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/YoeB-YefM
Location 3881386..3881891 Replicon chromosome
Accession NZ_CP116672
Organism Xanthomonas hortorum pv. pelargonii strain 305

Toxin (Protein)


Gene name relE Uniprot ID V7ZHE2
Locus tag PML25_RS16065 Protein ID WP_023902910.1
Coordinates 3881634..3881891 (+) Length 86 a.a.

Antitoxin (Protein)


Gene name relE Uniprot ID A0A6V7E8M0
Locus tag PML25_RS16060 Protein ID WP_043888988.1
Coordinates 3881386..3881637 (+) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PML25_RS16040 (PML25_16040) 3876759..3877913 - 1155 WP_168959477.1 2-methylcitrate synthase -
PML25_RS16045 (PML25_16045) 3877989..3878885 - 897 WP_168959476.1 methylisocitrate lyase -
PML25_RS16050 (PML25_16050) 3879013..3880632 + 1620 WP_180336594.1 propionate catabolism operon regulatory protein PrpR -
PML25_RS16055 (PML25_16055) 3880875..3881201 - 327 WP_168959474.1 hypothetical protein -
PML25_RS16060 (PML25_16060) 3881386..3881637 + 252 WP_043888988.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
PML25_RS16065 (PML25_16065) 3881634..3881891 + 258 WP_023902910.1 Txe/YoeB family addiction module toxin Toxin
PML25_RS16075 (PML25_16075) 3882400..3882753 - 354 WP_003483889.1 PilZ domain-containing protein -
PML25_RS16080 (PML25_16080) 3882750..3883709 - 960 WP_168959473.1 DNA polymerase III subunit delta' -
PML25_RS16085 (PML25_16085) 3883706..3884767 - 1062 WP_233366604.1 endolytic transglycosylase MltG -
PML25_RS16090 (PML25_16090) 3884840..3886195 - 1356 WP_168959472.1 aminodeoxychorismate synthase component I -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(2-84)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-74)


Sequences

Toxin        


Download         Length: 86 a.a.        Molecular weight: 10170.68 Da        Isoelectric Point: 9.6587

>T269093 WP_023902910.1 NZ_CP116672:3881634-3881891 [Xanthomonas hortorum pv. pelargonii]
VILQFADNAWEDYLYWQQTDKKMLKRINELIKAIQRDPFQGIGKPEPLRHALAGYWSRRINDEHRIVYKAENGILLIAQA
RYHYA

Download         Length: 258 bp

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9269.50 Da        Isoelectric Point: 4.6536

>AT269093 WP_043888988.1 NZ_CP116672:3881386-3881637 [Xanthomonas hortorum pv. pelargonii]
MDTITYSAARASLADTMDRVVNDHEPVIITRSGERAVVMLSLEDYKAMEETAYLLRSPKSAQRLLESIAQLEAGRGKERE
LAE

Download         Length: 252 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A6V7E8N0

Antitoxin

Source ID Structure
AlphaFold DB A0A6V7E8M0

References