Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RelE-MqsA
Location 3862151..3862850 Replicon chromosome
Accession NZ_CP116621
Organism Proteus terrae strain TP22

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag ONR67_RS17765 Protein ID WP_075671320.1
Coordinates 3862151..3862537 (+) Length 129 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag ONR67_RS17770 Protein ID WP_075671318.1
Coordinates 3862530..3862850 (+) Length 107 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
ONR67_RS17750 (ONR67_17750) 3858189..3858773 - 585 WP_109419307.1 DNA-3-methyladenine glycosylase I -
ONR67_RS17755 (ONR67_17755) 3859012..3859917 + 906 WP_004246832.1 glycine--tRNA ligase subunit alpha -
ONR67_RS17760 (ONR67_17760) 3859927..3861999 + 2073 WP_271976618.1 glycine--tRNA ligase subunit beta -
ONR67_RS17765 (ONR67_17765) 3862151..3862537 + 387 WP_075671320.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
ONR67_RS17770 (ONR67_17770) 3862530..3862850 + 321 WP_075671318.1 helix-turn-helix domain-containing protein Antitoxin
ONR67_RS17775 (ONR67_17775) 3862918..3863238 - 321 WP_196576345.1 hypothetical protein -
ONR67_RS17780 (ONR67_17780) 3863344..3864630 - 1287 WP_075671314.1 DUF3748 domain-containing protein -
ONR67_RS17785 (ONR67_17785) 3864767..3865384 + 618 WP_006534609.1 trimeric intracellular cation channel family protein -
ONR67_RS17790 (ONR67_17790) 3865690..3866313 + 624 WP_006534608.1 guanylate kinase -
ONR67_RS17795 (ONR67_17795) 3866368..3866643 + 276 WP_004246820.1 DNA-directed RNA polymerase subunit omega -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-2

(1-125)

Antitoxin

Cro/C1-type helix-turn-helix domain

(50-96)


Sequences

Toxin        


Download         Length: 129 a.a.        Molecular weight: 14358.75 Da        Isoelectric Point: 10.0463

>T269089 WP_075671320.1 NZ_CP116621:3862151-3862537 [Proteus terrae]
MVIYKTKMFKNSFKKMPINDAALIDIANEVYAGHFEADLGGGIIKKRICIHGKGKSSGIRTIIFYKQGSNLFFADGWKKS
HLSAKKSKEITDDELESYKDLAKDLFSATKNKIDKMVALGLLTEVKHD

Download         Length: 387 bp

Antitoxin


Download         Length: 107 a.a.        Molecular weight: 12068.99 Da        Isoelectric Point: 10.0482

>AT269089 WP_075671318.1 NZ_CP116621:3862530-3862850 [Proteus terrae]
MTDKMQEMLKFAQEMEVAGITDGESARRIAARIKAKELKERYAHLTPMNGEDIKRIREQNNISQSSLALILNMTKESVSK
WERNEIKPNGAALRLLNLIDNKAISI

Download         Length: 321 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References