Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) tacAT/GNAT-DUF1778
Location 2417949..2418694 Replicon chromosome
Accession NZ_CP116621
Organism Proteus terrae strain TP22

Toxin (Protein)


Gene name tacT Uniprot ID -
Locus tag ONR67_RS11395 Protein ID WP_075673025.1
Coordinates 2418203..2418694 (+) Length 164 a.a.

Antitoxin (Protein)


Gene name tacA Uniprot ID -
Locus tag ONR67_RS11390 Protein ID WP_075673024.1
Coordinates 2417949..2418215 (+) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
ONR67_RS11355 (ONR67_11355) 2413610..2414092 + 483 WP_006533151.1 flagellar basal body-associated protein FliL -
ONR67_RS11360 (ONR67_11360) 2414098..2415129 + 1032 WP_023581831.1 flagellar motor switch protein FliM -
ONR67_RS11365 (ONR67_11365) 2415122..2415532 + 411 WP_006533153.1 flagellar motor switch protein FliN -
ONR67_RS11370 (ONR67_11370) 2415536..2415982 + 447 WP_075673022.1 flagellar biosynthetic protein FliO -
ONR67_RS11375 (ONR67_11375) 2415982..2416752 + 771 WP_023581828.1 flagellar type III secretion system pore protein FliP -
ONR67_RS11380 (ONR67_11380) 2416768..2417037 + 270 WP_069367481.1 flagellar biosynthesis protein FliQ -
ONR67_RS11385 (ONR67_11385) 2417043..2417825 + 783 WP_099660619.1 flagellar biosynthetic protein FliR -
ONR67_RS11390 (ONR67_11390) 2417949..2418215 + 267 WP_075673024.1 DUF1778 domain-containing protein Antitoxin
ONR67_RS11395 (ONR67_11395) 2418203..2418694 + 492 WP_075673025.1 GNAT family N-acetyltransferase Toxin
ONR67_RS11400 (ONR67_11400) 2418780..2419724 - 945 WP_159241969.1 flagellar hook-associated protein FlgL -
ONR67_RS11405 (ONR67_11405) 2419756..2421399 - 1644 WP_159241968.1 flagellar hook-associated protein FlgK -
ONR67_RS11410 (ONR67_11410) 2421517..2422503 - 987 WP_159241967.1 flagellar assembly peptidoglycan hydrolase FlgJ -
ONR67_RS11415 (ONR67_11415) 2422503..2423609 - 1107 WP_075673029.1 flagellar basal body P-ring protein FlgI -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

GNAT domain

(22-150)

Antitoxin

Vibrio phage ICP1, Orf50

(2-87)


Sequences

Toxin        


Download         Length: 164 a.a.        Molecular weight: 18228.15 Da        Isoelectric Point: 10.3194

>T269085 WP_075673025.1 NZ_CP116621:2418203-2418694 [Proteus terrae]
MGKVTAPEPLSNSHEVADFYSSENVLDNWIKQRGLKNQFLGASRTFVVCEKNKKRVVGYYSLATGSVNHTEAMSHIRRNM
PDPIPVIILARLAVDKTFHGKGLGADLLRDAVLRCHHVAENIGVRAIMVHALTENAKHFYLHHGFKASSTQDKILFLALK
KKI

Download         Length: 492 bp

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 10111.62 Da        Isoelectric Point: 4.5256

>AT269085 WP_075673024.1 NZ_CP116621:2417949-2418215 [Proteus terrae]
MKADVQLNIRAKESQRALIDTAAEILHKSRTDFILETACQAAEDVILDRRTFNLNDAQYAEFIEIIDAPVDIDPALEKLL
MRKPLWEK

Download         Length: 267 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References