Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RelE-MqsA
Location 3784071..3784770 Replicon chromosome
Accession NZ_CP116620
Organism Proteus terrae strain CZP50

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag ONR71_RS17425 Protein ID WP_075671320.1
Coordinates 3784071..3784457 (+) Length 129 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag ONR71_RS17430 Protein ID WP_075671318.1
Coordinates 3784450..3784770 (+) Length 107 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
ONR71_RS17410 (ONR71_17410) 3780109..3780693 - 585 WP_159242124.1 DNA-3-methyladenine glycosylase I -
ONR71_RS17415 (ONR71_17415) 3780932..3781837 + 906 WP_004246832.1 glycine--tRNA ligase subunit alpha -
ONR71_RS17420 (ONR71_17420) 3781847..3783919 + 2073 WP_075671322.1 glycine--tRNA ligase subunit beta -
ONR71_RS17425 (ONR71_17425) 3784071..3784457 + 387 WP_075671320.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
ONR71_RS17430 (ONR71_17430) 3784450..3784770 + 321 WP_075671318.1 helix-turn-helix domain-containing protein Antitoxin
ONR71_RS17435 (ONR71_17435) 3784838..3785158 - 321 WP_075671316.1 hypothetical protein -
ONR71_RS17440 (ONR71_17440) 3785252..3786538 - 1287 WP_159242125.1 DUF3748 domain-containing protein -
ONR71_RS17445 (ONR71_17445) 3786675..3787292 + 618 WP_006534609.1 trimeric intracellular cation channel family protein -
ONR71_RS17450 (ONR71_17450) 3787598..3788221 + 624 WP_006534608.1 guanylate kinase -
ONR71_RS17455 (ONR71_17455) 3788276..3788551 + 276 WP_004246820.1 DNA-directed RNA polymerase subunit omega -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-2

(1-125)

Antitoxin

Cro/C1-type helix-turn-helix domain

(50-96)


Sequences

Toxin        


Download         Length: 129 a.a.        Molecular weight: 14358.75 Da        Isoelectric Point: 10.0463

>T269083 WP_075671320.1 NZ_CP116620:3784071-3784457 [Proteus terrae]
MVIYKTKMFKNSFKKMPINDAALIDIANEVYAGHFEADLGGGIIKKRICIHGKGKSSGIRTIIFYKQGSNLFFADGWKKS
HLSAKKSKEITDDELESYKDLAKDLFSATKNKIDKMVALGLLTEVKHD

Download         Length: 387 bp

Antitoxin


Download         Length: 107 a.a.        Molecular weight: 12068.99 Da        Isoelectric Point: 10.0482

>AT269083 WP_075671318.1 NZ_CP116620:3784450-3784770 [Proteus terrae]
MTDKMQEMLKFAQEMEVAGITDGESARRIAARIKAKELKERYAHLTPMNGEDIKRIREQNNISQSSLALILNMTKESVSK
WERNEIKPNGAALRLLNLIDNKAISI

Download         Length: 321 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References