Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) hipBA/HipA-couple_hipB
Location 3473915..3475656 Replicon chromosome
Accession NZ_CP116620
Organism Proteus terrae strain CZP50

Toxin (Protein)


Gene name hipA Uniprot ID -
Locus tag ONR71_RS16060 Protein ID WP_098941872.1
Coordinates 3473915..3475288 (+) Length 458 a.a.

Antitoxin (Protein)


Gene name hipB Uniprot ID -
Locus tag ONR71_RS16065 Protein ID WP_159241810.1
Coordinates 3475285..3475656 (+) Length 124 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

HipA-like, C-terminal

(174-418)

Antitoxin

Cro/C1-type helix-turn-helix domain

(48-103)


Sequences

Toxin        


Download         Length: 458 a.a.        Molecular weight: 52589.44 Da        Isoelectric Point: 4.6415

>T269081 WP_098941872.1 NZ_CP116620:3473915-3475288 [Proteus terrae]
MEKITLQAFLNQEWVDIAIINFPKYDRMLYASKYDITYPITELEYETSYSIEHLYQDDQHAVSINHPVELYFDDSGSPGW
LKFLDDIVPSGASRRYWLQYLDIAELSTEQQNYELLHHGTISPIGNLRVKESLPAPSPLNRNLFFTINDVKNRASDFLDY
AQRKGAAAGGATGAGGEAPKLLLRCNDNEEVWIDTYQDDISNLDKYYLVKFPRGSRSVVDCNILRTEYHFYHELTDMGFD
TIPIKDMRLEEGDNYPSLWLPRFDIKIENNKIIRLAMESVYSILNKAPGTTLYHETVIKELIDKINQSNMVTEFGFQFNT
ANFIIEWVRRDLLNIIFGNSDNHGRNTSLIRYNNAIYLAPIYDFAPMKADPEGIARTTKWGSHSEIGGEYNFINIADSLS
DLIAPEQLLNALQETAQQLLTLKERLEMRGVPTQILTMPSFGFDFIPNKLERWGLLP

Download         Length: 1374 bp

Antitoxin


Download         Length: 124 a.a.        Molecular weight: 13856.12 Da        Isoelectric Point: 10.6462

>AT269081 WP_159241810.1 NZ_CP116620:3475285-3475656 [Proteus terrae]
MNNVENKNHIDKFPTRASRKHQFVATTDRKQVISKIMAHLLFGEITQGEALKMLRIKVLGLNQDLYAKLINVSRKTLSEI
ENDRGNYSADIINKVFKPFGLKVGLVPSSPHILSSLLKESPSN

Download         Length: 372 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References