Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) tacAT/GNAT-DUF1778
Location 2352997..2353742 Replicon chromosome
Accession NZ_CP116620
Organism Proteus terrae strain CZP50

Toxin (Protein)


Gene name tacT Uniprot ID -
Locus tag ONR71_RS10850 Protein ID WP_159241970.1
Coordinates 2353251..2353742 (+) Length 164 a.a.

Antitoxin (Protein)


Gene name tacA Uniprot ID -
Locus tag ONR71_RS10845 Protein ID WP_075673024.1
Coordinates 2352997..2353263 (+) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
ONR71_RS10810 (ONR71_10810) 2348658..2349140 + 483 WP_006533151.1 flagellar basal body-associated protein FliL -
ONR71_RS10815 (ONR71_10815) 2349146..2350177 + 1032 WP_023581831.1 flagellar motor switch protein FliM -
ONR71_RS10820 (ONR71_10820) 2350170..2350580 + 411 WP_006533153.1 flagellar motor switch protein FliN -
ONR71_RS10825 (ONR71_10825) 2350584..2351030 + 447 WP_075673022.1 flagellar biosynthetic protein FliO -
ONR71_RS10830 (ONR71_10830) 2351030..2351800 + 771 WP_023581828.1 flagellar type III secretion system pore protein FliP -
ONR71_RS10835 (ONR71_10835) 2351816..2352085 + 270 WP_069367481.1 flagellar biosynthesis protein FliQ -
ONR71_RS10840 (ONR71_10840) 2352091..2352873 + 783 WP_099660619.1 flagellar biosynthetic protein FliR -
ONR71_RS10845 (ONR71_10845) 2352997..2353263 + 267 WP_075673024.1 DUF1778 domain-containing protein Antitoxin
ONR71_RS10850 (ONR71_10850) 2353251..2353742 + 492 WP_159241970.1 GNAT family N-acetyltransferase Toxin
ONR71_RS10855 (ONR71_10855) 2353828..2354772 - 945 WP_159241969.1 flagellar hook-associated protein FlgL -
ONR71_RS10860 (ONR71_10860) 2354804..2356447 - 1644 WP_159241968.1 flagellar hook-associated protein FlgK -
ONR71_RS10865 (ONR71_10865) 2356565..2357551 - 987 WP_159241967.1 flagellar assembly peptidoglycan hydrolase FlgJ -
ONR71_RS10870 (ONR71_10870) 2357551..2358657 - 1107 WP_159241966.1 flagellar basal body P-ring protein FlgI -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

GNAT domain

(22-148)

Antitoxin

Vibrio phage ICP1, Orf50

(2-87)


Sequences

Toxin        


Download         Length: 164 a.a.        Molecular weight: 18240.21 Da        Isoelectric Point: 10.3194

>T269079 WP_159241970.1 NZ_CP116620:2353251-2353742 [Proteus terrae]
MGKVTAPEPLSNSHEVADFYSSENVLDNWIKQRGLKNQFLGASRTFVVCEKNKKRVVGYYSLATGSVNHTEAMSHIRRNM
PDPIPVIILARLAVDKTFHGKGLGADLLRDAVLRCHHVAENIGVRAIMVHALTENAKHFYLHHGFKASSIQDKILFLALK
KKI

Download         Length: 492 bp

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 10111.62 Da        Isoelectric Point: 4.5256

>AT269079 WP_075673024.1 NZ_CP116620:2352997-2353263 [Proteus terrae]
MKADVQLNIRAKESQRALIDTAAEILHKSRTDFILETACQAAEDVILDRRTFNLNDAQYAEFIEIIDAPVDIDPALEKLL
MRKPLWEK

Download         Length: 267 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References