Detailed information of TA system TA269078

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): pmenTA/darT(toxin)
• Location: 3699747..3701458
• Replicon: chromosome
• Accession: NZ_CP116615
• Organism: Fontisphaera persica strain B-154

Toxin (Protein)

• Gene name: pmenT
• Uniprot ID: -
• Locus tag: NXS98_RS13890
• Protein ID: WP_283845617.1
• Coordinates: 3699747..3700385 (+)
• Length: 213 a.a.

Antitoxin (Protein)

• Gene name: pmenA
• Uniprot ID: -
• Locus tag: NXS98_RS13895
• Protein ID: WP_283845618.1
• Coordinates: 3700388..3701458 (+)
• Length: 357 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
NXS98_RS13870 (NXS98_13870)	3695402..3696097	+	696	WP_283845614.1	LUD domain-containing protein	-
NXS98_RS13880 (NXS98_13880)	3696537..3697040	+	504	WP_283845615.1	VanZ family protein	-
NXS98_RS13885 (NXS98_13885)	3697052..3699490	+	2439	WP_283845616.1	ComEC/Rec2 family competence protein	-
NXS98_RS13890 (NXS98_13890)	3699747..3700385	+	639	WP_283845617.1	DUF4433 domain-containing protein	Toxin
NXS98_RS13895 (NXS98_13895)	3700388..3701458	+	1071	WP_283845618.1	macro domain-containing protein	Antitoxin
NXS98_RS13900 (NXS98_13900)	3701641..3704211	+	2571	WP_283845619.1	GH116 family glycosyl hydrolase	-
NXS98_RS13905 (NXS98_13905)	3704346..3705713	+	1368	WP_283845620.1	PQQ-like beta-propeller repeat protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• ssDNA thymidine ADP-ribosyltransferase, DarT (12-212)

Antitoxin

• Macro domain (18-130)

Sequences

Toxin

Protein

• Length: 213 a.a.
• Molecular weight: 24249.86 Da
• Isoelectric Point: 8.6407

>T269078 WP_283845617.1 NZ_CP116615:3699747-3700385 [Fontisphaera persica]
MSALTPQNALIFRITHLANIPWLLDHGLHCQSAPQRDPHFHALGNPELIARRQHRRVPIAPGGTLADYVPFYFTPYSIML
YNIKTGHGGVPHVANEQIVFLVSSLRRVAEMGIAFVFTDRHAYVQTAAYYNSLEDLAQVDWKLLQSRDFSNDPNDPGKKE
RYQAEALVYRHLPMAGLMSLVCHNPEVEAYLCQEVARRNLSLKIAVRPRWYF

Nucleotide

• Length: 639 bp

Antitoxin

Protein

• Length: 357 a.a.
• Molecular weight: 40345.64 Da
• Isoelectric Point: 8.6971

>AT269078 WP_283845618.1 NZ_CP116615:3700388-3701458 [Fontisphaera persica]
MITFQQGNLLEAEVEALVNTVNTVGVMGKGIALMFKERYPENFRAYAQACKAGKVRPGRMFVTATGELTGPRWIINFPTK
EHWRNPSRLEWIAAGLEDLVRVIREKNIRSVALPPLGCGQGGLDWNQVRPLIESILGQLSEVQVIAFEPTVQYQNVAKHG
GVAQLTVPRALMAETIRRYWVLGIECTLLEIHKLAWFLSQAIQRRNLPDVLDLRFQADRYGPYSHRLNHLLNALDGSYLR
ANKRVADCTPCDTIAFADEKAETVALFLRRTESRPYLPVLDDVDQWIDGYQSPLGMELLATVHWLLVQERCAPEVRALRE
ALARWPGGKDAGLRKNRLFQDHHLAAAIERLRPLIN

Nucleotide

• Length: 1071 bp