269063

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) tsbAT/-
Location 1023746..1024541 Replicon chromosome
Accession NZ_CP116597
Organism Staphylococcus sp. NRL 22/194

Toxin (Protein)


Gene name tsbT Uniprot ID -
Locus tag PNR82_RS05135 Protein ID WP_243589016.1
Coordinates 1024368..1024541 (+) Length 58 a.a.

Antitoxin (Protein)


Gene name tsbA Uniprot ID -
Locus tag PNR82_RS05130 Protein ID WP_243589015.1
Coordinates 1023746..1024345 (+) Length 200 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PNR82_RS05110 1019638..1021092 + 1455 WP_243589011.1 ABC transporter substrate-binding protein/permease -
PNR82_RS05115 1021085..1021807 + 723 WP_243589012.1 amino acid ABC transporter ATP-binding protein -
PNR82_RS05120 1021968..1023094 + 1127 Protein_974 tRNA epoxyqueuosine(34) reductase QueG -
PNR82_RS05125 1023095..1023565 + 471 WP_243589014.1 tRNA (uridine(34)/cytosine(34)/5- carboxymethylaminomethyluridine(34)-2'-O)- methyltransferase TrmL -
PNR82_RS05130 1023746..1024345 + 600 WP_243589015.1 glucosamine-6-phosphate isomerase Antitoxin
PNR82_RS05135 1024368..1024541 + 174 WP_243589016.1 SAS053 family protein Toxin
PNR82_RS05140 1024722..1025114 + 393 WP_243589017.1 hypothetical protein -
PNR82_RS05145 1025251..1026636 + 1386 WP_243589018.1 class II fumarate hydratase -
PNR82_RS05150 1026699..1027520 - 822 WP_243603614.1 RluA family pseudouridine synthase -
PNR82_RS05155 1027732..1028849 + 1118 Protein_981 GAF domain-containing sensor histidine kinase -
PNR82_RS05160 1028868..1029490 + 623 Protein_982 response regulator transcription factor -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Glucosamine-6-phosphate isomerase

(130-195)


Sequences

Toxin        


Download         Length: 58 a.a.        Molecular weight: 6726.17 Da        Isoelectric Point: 3.9487

>T269063 WP_243589016.1 NZ_CP116597:1024368-1024541 [Staphylococcus sp. NRL 22/194]
MSDKKETELNYHEEENAMVQDLDDLKELGKEMEQISEKNDEEKLNQSHDSDVRSDLD

Download         Length: 174 bp

Antitoxin


Download         Length: 200 a.a.        Molecular weight: 22463.45 Da        Isoelectric Point: 4.8518

>AT269063 WP_243589015.1 NZ_CP116597:1023746-1024345 [Staphylococcus sp. NRL 22/194]
MAMNFKVFNDVDQVAQFTADIIRKQFNNNPTTIAGLHLERETAPVLDELKKDVDRNPVDFSQVNILDYDDNRSYYEALGV
PSGQIYPINLDDDATSLIDDKIKTKENKGKLILQVTSIDEKGSLNVNIRQGLMKAREVVLVITGGQKREFVKKLYEENGK
SSFEPADLKVHRMVTVVLDRAAAEGLPEDVKEYFTAHFA

Download         Length: 600 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References