Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | hicAB/- |
Location | 1332282..1332871 | Replicon | chromosome |
Accession | NZ_CP116490 | ||
Organism | Haemophilus influenzae strain 93P10H1 |
Toxin (Protein)
Gene name | hicA | Uniprot ID | Q4QL51 |
Locus tag | BV187_RS06585 | Protein ID | WP_005653200.1 |
Coordinates | 1332282..1332530 (+) | Length | 83 a.a. |
Antitoxin (Protein)
Gene name | hicB | Uniprot ID | Q4QL50 |
Locus tag | BV187_RS06590 | Protein ID | WP_005653201.1 |
Coordinates | 1332527..1332871 (+) | Length | 115 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
BV187_RS06560 (BV187_1329) | 1327762..1328394 | + | 633 | WP_011272461.1 | energy-coupling factor transporter transmembrane protein EcfT | - |
BV187_RS06565 (BV187_1330) | 1328396..1329022 | + | 627 | WP_012054430.1 | energy-coupling factor ABC transporter ATP-binding protein | - |
BV187_RS06570 (BV187_1331) | 1329129..1330319 | - | 1191 | WP_005657030.1 | amino acid aminotransferase | - |
BV187_RS06575 (BV187_1332) | 1330459..1331547 | - | 1089 | WP_005686592.1 | 5-(carboxyamino)imidazole ribonucleotide synthase | - |
BV187_RS06580 (BV187_1333) | 1331617..1332111 | - | 495 | WP_005653194.1 | 5-(carboxyamino)imidazole ribonucleotide mutase | - |
BV187_RS06585 (BV187_1334) | 1332282..1332530 | + | 249 | WP_005653200.1 | type II toxin-antitoxin system HicA family toxin | Toxin |
BV187_RS06590 (BV187_1335) | 1332527..1332871 | + | 345 | WP_005653201.1 | type II toxin-antitoxin system HicB family antitoxin | Antitoxin |
BV187_RS06595 (BV187_1336) | 1332915..1335524 | + | 2610 | WP_012054428.1 | aminopeptidase N | - |
BV187_RS06600 (BV187_1337) | 1335596..1336210 | - | 615 | WP_005657019.1 | riboflavin synthase | - |
BV187_RS06605 (BV187_1338) | 1336254..1337648 | + | 1395 | WP_005657016.1 | sodium-coupled multidrug efflux MATE transporter HmrM | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
---|
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
---|
Structures
Toxin
Source | ID | Structure |
---|---|---|
AlphaFold DB | A0A5M6BP03 |
Antitoxin
Source | ID | Structure |
---|---|---|
AlphaFold DB | A0A0M1GMF9 |