268771

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) VapXD/-
Location 526897..527234 Replicon chromosome
Accession NZ_CP116489
Organism Haemophilus influenzae strain 93P28H1

Toxin (Protein)


Gene name VapD Uniprot ID A0A2R3FLH7
Locus tag BV189_RS02575 Protein ID WP_005686917.1
Coordinates 526897..527034 (-) Length 46 a.a.

Antitoxin (Protein)


Gene name VapX Uniprot ID A0A0M1GIA6
Locus tag BV189_RS02580 Protein ID WP_005649350.1
Coordinates 527043..527234 (-) Length 64 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
BV189_RS02555 (BV189_0523) 522088..523758 - 1671 WP_005686908.1 fructose-specific PTS transporter subunit EIIC -
BV189_RS02560 (BV189_0524) 523760..524701 - 942 WP_005686910.1 1-phosphofructokinase -
BV189_RS02565 (BV189_0525) 524703..526202 - 1500 WP_005686912.1 fused PTS fructose transporter subunit IIA/HPr protein -
BV189_RS02570 (BV189_0526) 526274..526804 - 531 WP_005686915.1 hypothetical protein -
BV189_RS02575 (BV189_0527) 526897..527034 - 138 WP_005686917.1 hypothetical protein Toxin
BV189_RS02580 (BV189_0528) 527043..527234 - 192 WP_005649350.1 DUF5397 domain-containing protein Antitoxin
BV189_RS02585 (BV189_0529) 527306..528604 - 1299 WP_032821624.1 hemolysin family protein -
BV189_RS02590 (BV189_0530) 528655..529179 - 525 WP_005686921.1 DUF1523 family protein -
BV189_RS02595 (BV189_0531) 529206..529988 - 783 WP_005686923.1 YchF/TatD family DNA exonuclease -
BV189_RS02600 (BV189_0532) 530043..531026 - 984 WP_005686925.1 DNA polymerase III subunit delta' -
BV189_RS02605 (BV189_0533) 531023..531655 - 633 WP_005686927.1 dTMP kinase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Protein of unknown function DUF5397

(1-63)


Sequences

Toxin        


Download         Length: 46 a.a.        Molecular weight: 5415.04 Da        Isoelectric Point: 4.4640

>T268771 WP_005686917.1 NZ_CP116489:c527034-526897 [Haemophilus influenzae]
MYAIAFDLVVKDTQDYHPKGVQEAYTDIRAFRIEQWSDFTDFIRN

Download         Length: 138 bp

Antitoxin


Download         Length: 64 a.a.        Molecular weight: 7047.02 Da        Isoelectric Point: 3.9930

>AT268771 WP_005649350.1 NZ_CP116489:c527234-527043 [Haemophilus influenzae]
MELRQQIPTGCIKQFGQFGVPYVVGEVAEFLPDGDVLVNITLLQSGEKDIYRLSHLLEDPEAE

Download         Length: 192 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2R3FLH7

Antitoxin

Source ID Structure
AlphaFold DB A0A0M1GIA6

References