Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-StbC
Location 5650238..5650911 Replicon chromosome
Accession NZ_CP116478
Organism Pseudomonas syringae pv. actinidiae strain PSA.AH.01

Toxin (Protein)


Gene name vapC Uniprot ID A0A2V0QPW6
Locus tag PHA47_RS25210 Protein ID WP_017684243.1
Coordinates 5650492..5650911 (+) Length 140 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID Q48B52
Locus tag PHA47_RS25205 Protein ID WP_003381346.1
Coordinates 5650238..5650495 (+) Length 86 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PHA47_RS25185 (PHA47_25185) 5646440..5646634 - 195 WP_017684246.1 hypothetical protein -
PHA47_RS25190 (PHA47_25190) 5647192..5648124 + 933 WP_020308919.1 XopAH/AvrB family type III secretion system effector -
PHA47_RS25195 (PHA47_25195) 5648933..5649187 - 255 WP_003381350.1 hypothetical protein -
PHA47_RS25200 (PHA47_25200) 5649235..5649891 - 657 WP_017684244.1 hypothetical protein -
PHA47_RS25205 (PHA47_25205) 5650238..5650495 + 258 WP_003381346.1 Arc family DNA-binding protein Antitoxin
PHA47_RS25210 (PHA47_25210) 5650492..5650911 + 420 WP_017684243.1 type II toxin-antitoxin system VapC family toxin Toxin
PHA47_RS25215 (PHA47_25215) 5650952..5651585 + 634 Protein_4980 recombinase family protein -
PHA47_RS25220 (PHA47_25220) 5651860..5652795 + 936 WP_017704392.1 AvrD family protein -
PHA47_RS25225 (PHA47_25225) 5653136..5653783 + 648 WP_017703697.1 histidine phosphatase family protein -
PHA47_RS25230 (PHA47_25230) 5654022..5654849 + 828 WP_003381339.1 TauD/TfdA family dioxygenase -
PHA47_RS25235 (PHA47_25235) 5654867..5655901 + 1035 WP_017684240.1 sulfotransferase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 5616466..5652795 36329


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(2-124)

Antitoxin

Arc-like DNA binding domain

(5-46)


Sequences

Toxin        


Download         Length: 140 a.a.        Molecular weight: 15152.46 Da        Isoelectric Point: 4.7010

>T268737 WP_017684243.1 NZ_CP116478:5650492-5650911 [Pseudomonas syringae pv. actinidiae]
MILLDTNVISEPQRREPNAHVLDWIDAQALETLYLSTITVAELRAGIALMPVGKRQDSLRENLEKHLLPMFANRVLSFDM
TCTKAYAELLAKSRAAGLAIETADAFIAAIALANGFTVATRDTGPFEAAGLNVINPWEA

Download         Length: 420 bp

Antitoxin


Download         Length: 86 a.a.        Molecular weight: 9401.62 Da        Isoelectric Point: 9.0330

>AT268737 WP_003381346.1 NZ_CP116478:5650238-5650495 [Pseudomonas syringae pv. actinidiae]
VANVNVRNLPDEVHRAIRIQAALHGRSTEAEIRDILERAARPEGRVKLGSFLASIAREVGGLTDKEHTLFENTRITSPAR
AVSFE

Download         Length: 258 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2V0QPW6

Antitoxin

Source ID Structure
AlphaFold DB Q48B52

References