Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RHH(antitoxin)
Location 1161300..1161841 Replicon chromosome
Accession NZ_CP116478
Organism Pseudomonas syringae pv. actinidiae strain PSA.AH.01

Toxin (Protein)


Gene name relE Uniprot ID A0A0K8LVV5
Locus tag PHA47_RS05190 Protein ID WP_017683357.1
Coordinates 1161300..1161575 (-) Length 92 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID A0A0K8LU58
Locus tag PHA47_RS05195 Protein ID WP_003382249.1
Coordinates 1161575..1161841 (-) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PHA47_RS05170 (PHA47_05170) 1156425..1157456 - 1032 WP_020312848.1 TRAP transporter substrate-binding protein -
PHA47_RS05175 (PHA47_05175) 1157513..1158397 - 885 WP_003380378.1 SMP-30/gluconolactonase/LRE family protein -
PHA47_RS05180 (PHA47_05180) 1158457..1159281 - 825 WP_003380380.1 NAD(P)-dependent oxidoreductase -
PHA47_RS05185 (PHA47_05185) 1159460..1160728 - 1269 WP_007244158.1 OprD family porin -
PHA47_RS05190 (PHA47_05190) 1161300..1161575 - 276 WP_017683357.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
PHA47_RS05195 (PHA47_05195) 1161575..1161841 - 267 WP_003382249.1 ribbon-helix-helix domain-containing protein Antitoxin
PHA47_RS05200 (PHA47_05200) 1162006..1163928 - 1923 WP_017683359.1 methyl-accepting chemotaxis protein -
PHA47_RS05205 (PHA47_05205) 1164287..1166167 + 1881 WP_003382247.1 methyl-accepting chemotaxis protein -
PHA47_RS05210 (PHA47_05210) 1166295..1166558 - 264 WP_017683360.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Genomic island - - 1151894..1161841 9947


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-90)

Antitoxin

Ribbon-helix-helix protein, CopG

(8-45)


Sequences

Toxin        


Download         Length: 92 a.a.        Molecular weight: 10770.41 Da        Isoelectric Point: 7.0123

>T268735 WP_017683357.1 NZ_CP116478:c1161575-1161300 [Pseudomonas syringae pv. actinidiae]
MELMWTSKTLSDVTRLYDFLAVANQPAAAQTAQKLTAAPIMLLSNPRIGERLEEFEPRDVRRIQIGRYEMRYEIVDSTIY
LLRLWHTREDR

Download         Length: 276 bp

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 9934.24 Da        Isoelectric Point: 5.7066

>AT268735 WP_003382249.1 NZ_CP116478:c1161841-1161575 [Pseudomonas syringae pv. actinidiae]
MTTKTRSVTAHIPEQLAEKVDLMAERLERSKNWIVKQALSAWIDQEEERSRLTREALADVDAGRVIDHQAVQAWADSLST
ATPLPVPR

Download         Length: 267 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A0K8LVV5

Antitoxin

Source ID Structure
AlphaFold DB A0A0K8LU58

References