Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-YafN
Location 4265981..4266516 Replicon chromosome
Accession NZ_CP116477
Organism Pectobacterium sp. A5351

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag O1Q74_RS19655 Protein ID WP_271875157.1
Coordinates 4266229..4266516 (+) Length 96 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID Q6DB37
Locus tag O1Q74_RS19650 Protein ID WP_010281712.1
Coordinates 4265981..4266232 (+) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
O1Q74_RS19635 (O1Q74_19635) 4262605..4263639 + 1035 WP_271875152.1 putative FMN-dependent luciferase-like monooxygenase -
O1Q74_RS19640 (O1Q74_19640) 4263636..4264769 + 1134 WP_271875153.1 alkylhydroperoxidase domain protein -
O1Q74_RS19645 (O1Q74_19645) 4264820..4265725 - 906 WP_271875154.1 siderophore-interacting protein -
O1Q74_RS19650 (O1Q74_19650) 4265981..4266232 + 252 WP_010281712.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
O1Q74_RS19655 (O1Q74_19655) 4266229..4266516 + 288 WP_271875157.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
O1Q74_RS19660 (O1Q74_19660) 4266611..4267963 - 1353 WP_271875158.1 glutathione-disulfide reductase -
O1Q74_RS19665 (O1Q74_19665) 4268092..4268934 - 843 WP_271875159.1 23S rRNA (adenine(2030)-N(6))-methyltransferase RlmJ -
O1Q74_RS19670 (O1Q74_19670) 4269336..4269629 + 294 WP_271875161.1 DUF2623 family protein -
O1Q74_RS19675 (O1Q74_19675) 4269639..4270460 - 822 WP_271875163.1 energy transducer TonB -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(5-84)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 96 a.a.        Molecular weight: 11088.14 Da        Isoelectric Point: 10.3856

>T268732 WP_271875157.1 NZ_CP116477:4266229-4266516 [Pectobacterium sp. A5351]
MSYSVKFREDALKEWLKLDKTIQQQFAKKLKKCCENPHIPSAKLRGMKDCYRIKLRASGFRLVYEVIDDVLVIAVVAVGK
RERSGVYHLASERMR

Download         Length: 288 bp

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9117.47 Da        Isoelectric Point: 4.0637

>AT268732 WP_010281712.1 NZ_CP116477:4265981-4266232 [Pectobacterium sp. A5351]
MPNIILSDTSASVSELKKNPMATVNAGDGLPVAILNRNQPAFYCIPADLYEKMLDALDDQELVKLIGERKNQPLVDVDLD
SFL

Download         Length: 252 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB A0A0M2EZP0

References