Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type IV Classification (family/domain) sdenTA/AbiEii(toxin)
Location 4215988..4217426 Replicon chromosome
Accession NZ_CP116477
Organism Pectobacterium sp. A5351

Toxin (Protein)


Gene name sdenT Uniprot ID -
Locus tag O1Q74_RS19425 Protein ID WP_271875116.1
Coordinates 4215988..4216875 (-) Length 296 a.a.

Antitoxin (Protein)


Gene name sdenA Uniprot ID -
Locus tag O1Q74_RS19430 Protein ID WP_271875117.1
Coordinates 4216902..4217426 (-) Length 175 a.a.

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
O1Q74_RS19405 (O1Q74_19405) 4211600..4212463 + 864 WP_039278589.1 YicC/YloC family endoribonuclease -
O1Q74_RS19410 (O1Q74_19410) 4212650..4213909 + 1260 WP_271875114.1 site-specific integrase -
O1Q74_RS19415 (O1Q74_19415) 4214164..4214373 + 210 Protein_3766 IS630 family transposase -
O1Q74_RS19420 (O1Q74_19420) 4214948..4215772 + 825 WP_271875115.1 DNA damage-inducible protein D -
O1Q74_RS19425 (O1Q74_19425) 4215988..4216875 - 888 WP_271875116.1 nucleotidyl transferase AbiEii/AbiGii toxin family protein Toxin
O1Q74_RS19430 (O1Q74_19430) 4216902..4217426 - 525 WP_271875117.1 hypothetical protein Antitoxin
O1Q74_RS19435 (O1Q74_19435) 4218034..4219397 + 1364 WP_271873361.1 IS3 family transposase -
O1Q74_RS19440 (O1Q74_19440) 4219949..4220176 + 228 WP_271875118.1 hypothetical protein -
O1Q74_RS19445 (O1Q74_19445) 4220398..4220943 - 546 WP_271875119.1 hypothetical protein -
O1Q74_RS19450 (O1Q74_19450) 4221254..4221640 + 387 WP_271875120.1 hypothetical protein -
O1Q74_RS19455 (O1Q74_19455) 4221678..4221764 + 87 WP_271879000.1 DUF596 domain-containing protein -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 4180959..4219397 38438


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin

(36-265)

Antitoxin


No domain identified.



Sequences


Toxin        


Download         Length: 296 a.a.        Molecular weight: 34032.83 Da        Isoelectric Point: 5.1252

>T268731 WP_271875116.1 NZ_CP116477:c4216875-4215988 [Pectobacterium sp. A5351]
MLKQQIRQIVQSNPDYAAVTPVIEKEILHHDIMDVLIKQGVMQRLTFIGGTSLRMCYNSSRLSEDLDFNGGHDFQPSAFE
GLESEIQTYIQNKYETEVWVNKPSGEQQGDTVSWKMSIVKEANRPDLPRQKMHIDVCAIPSFDIEKRPLINHYDIVVPTE
GILVPVQSLQETLADKLIALAYRARRIKPRDIWDIVWVKQRGIDLSKTLVEKKLTARQEQTEDFRQALSIQLAKLMSEDE
VRDDFNMEMSRFIPKQIKERTLDNPEYWAYVQGEVHATASELLNDGTPKNPFDMG

Download         Length: 888 bp


Antitoxin


Download         Length: 175 a.a.        Molecular weight: 19319.41 Da        Isoelectric Point: 9.0511

>AT268731 WP_271875117.1 NZ_CP116477:c4217426-4216902 [Pectobacterium sp. A5351]
MAKSDELLNALAKAVNAGGGIHSVTELAFMQGVPCDSAFRKFLADCVKKGLLRRVVKGFYESVITPPEPETAIYKTIKKL
RSGVLNYISLESQLSHTGDISQVVMGRVTVVTKGRSGCFDTPYGVIELTHTKKSVEQIAPNLYYDPDIKMYRAYKEQAIA
DLKHCHRNLHMLES

Download         Length: 525 bp


Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure


Antitoxin

Source ID Structure

References