Detailed information of TA system
Overview
TA module
| Type | IV | Classification (family/domain) | sdenTA/AbiEii(toxin) |
| Location | 4215988..4217426 | Replicon | chromosome |
| Accession | NZ_CP116477 | ||
| Organism | Pectobacterium sp. A5351 | ||
Toxin (Protein)
| Gene name | sdenT | Uniprot ID | - |
| Locus tag | O1Q74_RS19425 | Protein ID | WP_271875116.1 |
| Coordinates | 4215988..4216875 (-) | Length | 296 a.a. |
Antitoxin (Protein)
| Gene name | sdenA | Uniprot ID | - |
| Locus tag | O1Q74_RS19430 | Protein ID | WP_271875117.1 |
| Coordinates | 4216902..4217426 (-) | Length | 175 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| O1Q74_RS19405 (O1Q74_19405) | 4211600..4212463 | + | 864 | WP_039278589.1 | YicC/YloC family endoribonuclease | - |
| O1Q74_RS19410 (O1Q74_19410) | 4212650..4213909 | + | 1260 | WP_271875114.1 | site-specific integrase | - |
| O1Q74_RS19415 (O1Q74_19415) | 4214164..4214373 | + | 210 | Protein_3766 | IS630 family transposase | - |
| O1Q74_RS19420 (O1Q74_19420) | 4214948..4215772 | + | 825 | WP_271875115.1 | DNA damage-inducible protein D | - |
| O1Q74_RS19425 (O1Q74_19425) | 4215988..4216875 | - | 888 | WP_271875116.1 | nucleotidyl transferase AbiEii/AbiGii toxin family protein | Toxin |
| O1Q74_RS19430 (O1Q74_19430) | 4216902..4217426 | - | 525 | WP_271875117.1 | hypothetical protein | Antitoxin |
| O1Q74_RS19435 (O1Q74_19435) | 4218034..4219397 | + | 1364 | WP_271873361.1 | IS3 family transposase | - |
| O1Q74_RS19440 (O1Q74_19440) | 4219949..4220176 | + | 228 | WP_271875118.1 | hypothetical protein | - |
| O1Q74_RS19445 (O1Q74_19445) | 4220398..4220943 | - | 546 | WP_271875119.1 | hypothetical protein | - |
| O1Q74_RS19450 (O1Q74_19450) | 4221254..4221640 | + | 387 | WP_271875120.1 | hypothetical protein | - |
| O1Q74_RS19455 (O1Q74_19455) | 4221678..4221764 | + | 87 | WP_271879000.1 | DUF596 domain-containing protein | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| - | inside | Prophage | - | - | 4180959..4219397 | 38438 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 296 a.a. Molecular weight: 34032.83 Da Isoelectric Point: 5.1252
>T268731 WP_271875116.1 NZ_CP116477:c4216875-4215988 [Pectobacterium sp. A5351]
MLKQQIRQIVQSNPDYAAVTPVIEKEILHHDIMDVLIKQGVMQRLTFIGGTSLRMCYNSSRLSEDLDFNGGHDFQPSAFE
GLESEIQTYIQNKYETEVWVNKPSGEQQGDTVSWKMSIVKEANRPDLPRQKMHIDVCAIPSFDIEKRPLINHYDIVVPTE
GILVPVQSLQETLADKLIALAYRARRIKPRDIWDIVWVKQRGIDLSKTLVEKKLTARQEQTEDFRQALSIQLAKLMSEDE
VRDDFNMEMSRFIPKQIKERTLDNPEYWAYVQGEVHATASELLNDGTPKNPFDMG
MLKQQIRQIVQSNPDYAAVTPVIEKEILHHDIMDVLIKQGVMQRLTFIGGTSLRMCYNSSRLSEDLDFNGGHDFQPSAFE
GLESEIQTYIQNKYETEVWVNKPSGEQQGDTVSWKMSIVKEANRPDLPRQKMHIDVCAIPSFDIEKRPLINHYDIVVPTE
GILVPVQSLQETLADKLIALAYRARRIKPRDIWDIVWVKQRGIDLSKTLVEKKLTARQEQTEDFRQALSIQLAKLMSEDE
VRDDFNMEMSRFIPKQIKERTLDNPEYWAYVQGEVHATASELLNDGTPKNPFDMG
Download Length: 888 bp
Antitoxin
Download Length: 175 a.a. Molecular weight: 19319.41 Da Isoelectric Point: 9.0511
>AT268731 WP_271875117.1 NZ_CP116477:c4217426-4216902 [Pectobacterium sp. A5351]
MAKSDELLNALAKAVNAGGGIHSVTELAFMQGVPCDSAFRKFLADCVKKGLLRRVVKGFYESVITPPEPETAIYKTIKKL
RSGVLNYISLESQLSHTGDISQVVMGRVTVVTKGRSGCFDTPYGVIELTHTKKSVEQIAPNLYYDPDIKMYRAYKEQAIA
DLKHCHRNLHMLES
MAKSDELLNALAKAVNAGGGIHSVTELAFMQGVPCDSAFRKFLADCVKKGLLRRVVKGFYESVITPPEPETAIYKTIKKL
RSGVLNYISLESQLSHTGDISQVVMGRVTVVTKGRSGCFDTPYGVIELTHTKKSVEQIAPNLYYDPDIKMYRAYKEQAIA
DLKHCHRNLHMLES
Download Length: 525 bp
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
Structures
Toxin
| Source | ID | Structure |
|---|
Antitoxin
| Source | ID | Structure |
|---|