Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) mosAT/AbiEii-AbiEi
Location 3292933..3294616 Replicon chromosome
Accession NZ_CP116477
Organism Pectobacterium sp. A5351

Toxin (Protein)


Gene name mosT Uniprot ID -
Locus tag O1Q74_RS15180 Protein ID WP_271874460.1
Coordinates 3292933..3293850 (-) Length 306 a.a.

Antitoxin (Protein)


Gene name mosA Uniprot ID -
Locus tag O1Q74_RS15185 Protein ID WP_271874461.1
Coordinates 3293843..3294616 (-) Length 258 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
O1Q74_RS15165 (O1Q74_15165) 3288077..3289255 - 1179 WP_271874457.1 site-specific integrase -
O1Q74_RS15170 (O1Q74_15170) 3289785..3290999 - 1215 WP_271874458.1 tyrosine-type recombinase/integrase -
O1Q74_RS15175 (O1Q74_15175) 3291385..3292704 + 1320 WP_271874459.1 site-specific integrase -
O1Q74_RS15180 (O1Q74_15180) 3292933..3293850 - 918 WP_271874460.1 nucleotidyl transferase AbiEii/AbiGii toxin family protein Toxin
O1Q74_RS15185 (O1Q74_15185) 3293843..3294616 - 774 WP_271874461.1 type IV toxin-antitoxin system AbiEi family antitoxin Antitoxin
O1Q74_RS15190 (O1Q74_15190) 3294744..3295799 - 1056 WP_271874463.1 hypothetical protein -
O1Q74_RS15195 (O1Q74_15195) 3295958..3296155 - 198 WP_271874464.1 AlpA family phage regulatory protein -
O1Q74_RS15200 (O1Q74_15200) 3296397..3296906 + 510 WP_271874465.1 hypothetical protein -
O1Q74_RS15205 (O1Q74_15205) 3296940..3297628 - 689 Protein_2950 site-specific integrase -
O1Q74_RS15210 (O1Q74_15210) 3297696..3297839 - 144 Protein_2951 IS3 family transposase -
O1Q74_RS15215 (O1Q74_15215) 3297906..3298928 + 1023 WP_271874467.1 IS110 family transposase -
O1Q74_RS15220 (O1Q74_15220) 3299151..3299267 - 117 Protein_2953 transposase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Nucleotidyl transferase AbiEii toxin, Type IV TA system

(14-277)

Antitoxin

Transcriptional regulator, AbiEi 3 antitoxin, Type IV TA system

(95-246)


Sequences

Toxin        


Download         Length: 306 a.a.        Molecular weight: 34829.02 Da        Isoelectric Point: 5.4255

>T268728 WP_271874460.1 NZ_CP116477:c3293850-3292933 [Pectobacterium sp. A5351]
MDKNSPYYRQVVLLMRALPLVATERCFALKGGTAINLFVRDFPRLSVDIDLAYISLESRDEALPNVRAALNRIAEILQQR
VDISAVLQTNNPDEMRIVVSSHEAQIKIEVSPVARGTLYPPEDRDVVDSVEDEFGFATIQVVSLADLYGGKLCAAMDRQH
PRDFYDVKMLLETQGIDRHIFNGFITYLLGHPRPFSEVLNPRWKDISELYAHEFNGMTFDAVSVEELNAIPKLMVNALKA
QFTQRDYDFLMSFKSGQPDWSLAPEDQIQHLPAVKWKLQNIGRMQKEKHIQALVKLEEVLAGWLR

Download         Length: 918 bp

Antitoxin


Download         Length: 258 a.a.        Molecular weight: 29375.07 Da        Isoelectric Point: 9.9248

>AT268728 WP_271874461.1 NZ_CP116477:c3294616-3293843 [Pectobacterium sp. A5351]
MASKLNWLLQNTDPGSLVVQSWLTKYGISPSLAHKYTQSNWLRKLRTGVYVRVGREPEWSDAVLCLQNQLSIPVHLAGLT
SLVYQGRSHYLQLKQQRIWLYVEEKAALPKWFREFPGVEWLLLSNQKLSQLDEKYLIDVEIKSKALKASVPELAAYELAD
VVPRCITFEHAAELFQGLVNLSPRKVEMLLRASRAVQTNRLYLFLADYYVHPWVKRIDKNSIDLGAGKRQIVAGGKLDKQ
YQITVPGKFINDGLSHG

Download         Length: 774 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References