Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) Hha-TomB/-
Location 3161064..3161689 Replicon chromosome
Accession NZ_CP116477
Organism Pectobacterium sp. A5351

Toxin (Protein)


Gene name Hha Uniprot ID C6DB72
Locus tag O1Q74_RS14655 Protein ID WP_005976087.1
Coordinates 3161486..3161689 (+) Length 68 a.a.

Antitoxin (Protein)


Gene name TomB Uniprot ID -
Locus tag O1Q74_RS14650 Protein ID WP_271874138.1
Coordinates 3161064..3161432 (+) Length 123 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
O1Q74_RS14635 (O1Q74_14635) 3158297..3159772 - 1476 Protein_2837 IS1182 family transposase -
O1Q74_RS14640 (O1Q74_14640) 3160059..3160307 + 249 WP_271874133.1 type B 50S ribosomal protein L31 -
O1Q74_RS14645 (O1Q74_14645) 3160325..3160468 + 144 WP_005976091.1 type B 50S ribosomal protein L36 -
O1Q74_RS14650 (O1Q74_14650) 3161064..3161432 + 369 WP_271874138.1 Hha toxicity modulator TomB Antitoxin
O1Q74_RS14655 (O1Q74_14655) 3161486..3161689 + 204 WP_005976087.1 HHA domain-containing protein Toxin
O1Q74_RS14665 (O1Q74_14665) 3162425..3162745 + 321 WP_271874142.1 MGMT family protein -
O1Q74_RS14670 (O1Q74_14670) 3162766..3163338 - 573 WP_271874143.1 YbaY family lipoprotein -
O1Q74_RS14675 (O1Q74_14675) 3163551..3164414 + 864 WP_271874145.1 acyl-CoA thioesterase II -
O1Q74_RS14680 (O1Q74_14680) 3164492..3165778 - 1287 WP_271874146.1 ammonium transporter AmtB -
O1Q74_RS14685 (O1Q74_14685) 3165818..3166156 - 339 WP_002208627.1 P-II family nitrogen regulator -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Haemolysin expression modulating, HHA

(8-64)

Antitoxin

Biofilm formation regulator YbaJ

(1-118)


Sequences

Toxin        


Download         Length: 68 a.a.        Molecular weight: 8145.52 Da        Isoelectric Point: 8.9008

>T268727 WP_005976087.1 NZ_CP116477:3161486-3161689 [Pectobacterium sp. A5351]
MKKIDYLMRLRKCTTIDTLERVIEKNKYELSNDELEMFFSAADHRLAELTMNKLYDKVPTAVWRYVR

Download         Length: 204 bp

Antitoxin


Download         Length: 123 a.a.        Molecular weight: 13979.72 Da        Isoelectric Point: 4.3689

>AT268727 WP_271874138.1 NZ_CP116477:3161064-3161432 [Pectobacterium sp. A5351]
MDEYTPKHYDIAQLRFLCENLCDESIATLGDSSHGWVNDPTSAINLQLNELIEHIATFILTFKIKYPNESELSEQVEKYL
DDTYVLFSNYGINDAELRCWQKSKAKLFGMFSGENVCTPAKT

Download         Length: 369 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A1D7Z3F0

Antitoxin

Source ID Structure

References