Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type VII Classification (family/domain) HepT-MntA/HepT(toxin)
Location 2924237..2925036 Replicon chromosome
Accession NZ_CP116477
Organism Pectobacterium sp. A5351

Toxin (Protein)


Gene name hepT Uniprot ID A0A7T5U992
Locus tag O1Q74_RS13560 Protein ID WP_039535340.1
Coordinates 2924617..2925036 (+) Length 140 a.a.

Antitoxin (Protein)


Gene name mntA Uniprot ID -
Locus tag O1Q74_RS13555 Protein ID WP_271873805.1
Coordinates 2924237..2924620 (+) Length 128 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
O1Q74_RS13540 (O1Q74_13540) 2919539..2920675 - 1137 WP_271873801.1 polysaccharide export protein -
O1Q74_RS13545 (O1Q74_13545) 2920801..2921880 - 1080 WP_271873802.1 UDP-N-acetylglucosamine--undecaprenyl-phosphate N-acetylglucosaminephosphotransferase -
O1Q74_RS13550 (O1Q74_13550) 2922537..2924123 + 1587 WP_271873803.1 TerC family protein -
O1Q74_RS13555 (O1Q74_13555) 2924237..2924620 + 384 WP_271873805.1 nucleotidyltransferase domain-containing protein Antitoxin
O1Q74_RS13560 (O1Q74_13560) 2924617..2925036 + 420 WP_039535340.1 DUF86 domain-containing protein Toxin
O1Q74_RS13565 (O1Q74_13565) 2925080..2926426 - 1347 WP_271873807.1 anaerobic C4-dicarboxylate transporter DcuC -
O1Q74_RS13570 (O1Q74_13570) 2926726..2928561 - 1836 WP_271873808.1 outer membrane assembly protein AsmA -
O1Q74_RS13575 (O1Q74_13575) 2928654..2929235 - 582 WP_015839565.1 dCTP deaminase -
O1Q74_RS13580 (O1Q74_13580) 2929360..2930001 - 642 WP_015839564.1 uridine kinase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Ribonuclease HepT-like

(13-130)

Antitoxin

Polymerase beta, nucleotidyltransferase

(4-93)


Sequences

Toxin        


Download         Length: 140 a.a.        Molecular weight: 16038.34 Da        Isoelectric Point: 6.9682

>T268726 WP_039535340.1 NZ_CP116477:2924617-2925036 [Pectobacterium sp. A5351]
MTDILLNKSSTIQRCLRRIREEFDTEEGFRQNFTKQDSVILNIQRACEAAIDIANYLIRIKQLGIPQSSRDSFALLAANQ
IITVDLSDNLQKMVGLRNIAVHDYQALNLDIVIHVISHRLSDFEHFIKQIARYSDSQHL

Download         Length: 420 bp

Antitoxin


Download         Length: 128 a.a.        Molecular weight: 14371.63 Da        Isoelectric Point: 5.2044

>AT268726 WP_271873805.1 NZ_CP116477:2924237-2924620 [Pectobacterium sp. A5351]
MFDKIVLTLKKQMPDIKIIYLFGSQATGNARADSDIDIAIMATRALDPVKRWELSNQLAKEVGHDVDLIDLLQASTVLKM
EIVRNGKLLYDAETAAGEFEMTTLSMYQHLQKERADIIRSFNQDLKA

Download         Length: 384 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A7T5U992

Antitoxin

Source ID Structure

References