Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PP_4151-4152/excise(antitoxin)
Location 951478..952514 Replicon chromosome
Accession NZ_CP116477
Organism Pectobacterium sp. A5351

Toxin (Protein)


Gene name PP_4152 Uniprot ID -
Locus tag O1Q74_RS04560 Protein ID WP_271876432.1
Coordinates 952011..952514 (+) Length 168 a.a.

Antitoxin (Protein)


Gene name PP_4151 Uniprot ID -
Locus tag O1Q74_RS04555 Protein ID WP_271876430.1
Coordinates 951478..951939 (+) Length 154 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
O1Q74_RS04535 (O1Q74_04530) 946525..947058 + 534 WP_225087113.1 RNA pyrophosphohydrolase -
O1Q74_RS04540 (O1Q74_04535) 947071..949317 + 2247 WP_271876427.1 phosphoenolpyruvate--protein phosphotransferase -
O1Q74_RS04545 (O1Q74_04540) 949547..950413 + 867 WP_271876428.1 prolipoprotein diacylglyceryl transferase -
O1Q74_RS04550 (O1Q74_04545) 950449..951243 + 795 WP_271876429.1 thymidylate synthase -
O1Q74_RS04555 (O1Q74_04550) 951478..951939 + 462 WP_271876430.1 helix-turn-helix domain-containing protein Antitoxin
O1Q74_RS04560 (O1Q74_04555) 952011..952514 + 504 WP_271876432.1 PIN domain-containing protein Toxin
O1Q74_RS04565 (O1Q74_04560) 952694..953197 + 504 WP_271876435.1 prepilin peptidase-dependent protein -
O1Q74_RS04570 (O1Q74_04565) 953191..953817 + 627 WP_271876437.1 prepilin peptidase-dependent protein -
O1Q74_RS04575 (O1Q74_04570) 953814..954269 + 456 WP_271876439.1 YgdB family protein -
O1Q74_RS04580 (O1Q74_04575) 954256..954651 + 396 WP_271878739.1 prepilin-type N-terminal cleavage/methylation domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(5-91)

Antitoxin

Helix-turn-helix domain, group 17

(84-132)


Sequences

Toxin        


Download         Length: 168 a.a.        Molecular weight: 18780.71 Da        Isoelectric Point: 4.6914

>T268723 WP_271876432.1 NZ_CP116477:952011-952514 [Pectobacterium sp. A5351]
MHLGLTGLYQPKWTALIQEEWQRNLLLNNADVTMDKLRNIEHLMNKALPDANVTGFEQLIPALVLPDADDRHVLAAAIRA
NAEVIVTANLKDFPATALLEFGVEAMHPDEFIADLFDLNSALVLKAVRTSRTAFRKPPFDVDEYLDCLLRQGLPMTVKEL
DAYRSLI

Download         Length: 504 bp

Antitoxin


Download         Length: 154 a.a.        Molecular weight: 17125.66 Da        Isoelectric Point: 6.0953

>AT268723 WP_271876430.1 NZ_CP116477:951478-951939 [Pectobacterium sp. A5351]
MKNTPLNSLSLPAPKEMEAAIRGQRQLATYLSTKLETQEISIQDAQDIAQKIELPTSALTLLMSILGELAAGNAVQIVPV
QAELTTQEAANILNVSRPHMVKLLEGGHLPFHKTGRHRRVLFADLMQYKEQRENESMQAMQELTDRSQELGFY

Download         Length: 462 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References