Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) ccdAB/CcdA(antitoxin)
Location 913455..913981 Replicon chromosome
Accession NZ_CP116477
Organism Pectobacterium sp. A5351

Toxin (Protein)


Gene name ccdB Uniprot ID -
Locus tag O1Q74_RS04360 Protein ID WP_271876359.1
Coordinates 913455..913760 (-) Length 102 a.a.

Antitoxin (Protein)


Gene name ccdA Uniprot ID -
Locus tag O1Q74_RS04365 Protein ID WP_271876362.1
Coordinates 913763..913981 (-) Length 73 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
O1Q74_RS04350 (O1Q74_04345) 910059..912068 + 2010 WP_271876356.1 helicase-related protein -
O1Q74_RS04355 (O1Q74_04350) 912070..913329 + 1260 WP_271876357.1 GIY-YIG nuclease family protein -
O1Q74_RS04360 (O1Q74_04355) 913455..913760 - 306 WP_271876359.1 type II toxin-antitoxin system toxin CcdB Toxin
O1Q74_RS04365 (O1Q74_04360) 913763..913981 - 219 WP_271876362.1 type II toxin-antitoxin system antitoxin CcdA Antitoxin
O1Q74_RS04370 (O1Q74_04365) 914040..914783 - 744 WP_271876364.1 MobC family replication-relaxation protein -
O1Q74_RS04375 (O1Q74_04370) 915206..915547 - 342 WP_271876367.1 hypothetical protein -
O1Q74_RS04380 (O1Q74_04375) 915687..915857 + 171 WP_271876369.1 hypothetical protein -
O1Q74_RS04385 (O1Q74_04380) 915999..917257 - 1259 Protein_839 integrase arm-type DNA-binding domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Integrative and Conjugative Element - - 901087..917425 16338


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin CcdB

(2-100)

Antitoxin

Post-segregation antitoxin CcdA

(2-72)


Sequences

Toxin        


Download         Length: 102 a.a.        Molecular weight: 11722.61 Da        Isoelectric Point: 4.8450

>T268722 WP_271876359.1 NZ_CP116477:c913760-913455 [Pectobacterium sp. A5351]
MQFIVYQHKITSHYKMFVDVQSDIVETPKRRMVIPLIESHHLSEKVNKTLFPLIRIDGEDYRLMTTELSSVPVEVIGEVI
ADLGDYADEIKDAINLMFWGI

Download         Length: 306 bp

Antitoxin


Download         Length: 73 a.a.        Molecular weight: 8178.08 Da        Isoelectric Point: 5.8316

>AT268722 WP_271876362.1 NZ_CP116477:c913981-913763 [Pectobacterium sp. A5351]
MKHRVSVTVDKDNYQVLSAAGVNISGLVNDAIGKEARRIRAEEWKKENREGMEEVAQFIAQNGSFADENRNW

Download         Length: 219 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References