268721

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) ccdAB/CcdA(antitoxin)
Location 889421..889947 Replicon chromosome
Accession NZ_CP116477
Organism Pectobacterium sp. A5351

Toxin (Protein)


Gene name ccdB Uniprot ID -
Locus tag O1Q74_RS04240 Protein ID WP_271876320.1
Coordinates 889421..889726 (-) Length 102 a.a.

Antitoxin (Protein)


Gene name ccdA Uniprot ID -
Locus tag O1Q74_RS04245 Protein ID WP_271876323.1
Coordinates 889729..889947 (-) Length 73 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
O1Q74_RS04215 (O1Q74_04210) 885293..885919 + 627 WP_271876313.1 protein-L-isoaspartate(D-aspartate) O-methyltransferase -
O1Q74_RS04220 (O1Q74_04215) 886344..887366 + 1023 WP_271876315.1 murein hydrolase activator NlpD -
O1Q74_RS04225 (O1Q74_04220) 887420..888412 + 993 WP_271876317.1 RNA polymerase sigma factor RpoS -
O1Q74_RS04230 (O1Q74_04225) 888522..888793 - 272 Protein_808 IS3 family transposase -
O1Q74_RS04235 (O1Q74_04230) 888840..889307 + 468 Protein_809 transposase -
O1Q74_RS04240 (O1Q74_04235) 889421..889726 - 306 WP_271876320.1 type II toxin-antitoxin system toxin CcdB Toxin
O1Q74_RS04245 (O1Q74_04240) 889729..889947 - 219 WP_271876323.1 type II toxin-antitoxin system antitoxin CcdA Antitoxin
O1Q74_RS04250 (O1Q74_04245) 890006..890230 - 225 Protein_812 molybdopterin-guanine dinucleotide biosynthesis protein MobC -
O1Q74_RS04255 (O1Q74_04250) 890300..890733 + 434 Protein_813 IS5 family transposase -
O1Q74_RS04260 (O1Q74_04255) 890913..892417 + 1505 Protein_814 type IV conjugative transfer system coupling protein TraD -
O1Q74_RS04265 (O1Q74_04260) 892417..892881 + 465 WP_271876325.1 DUF4400 domain-containing protein -
O1Q74_RS04270 (O1Q74_04265) 893057..893188 + 132 WP_258305550.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin CcdB

(2-100)

Antitoxin

Post-segregation antitoxin CcdA

(2-72)


Sequences

Toxin        


Download         Length: 102 a.a.        Molecular weight: 11839.76 Da        Isoelectric Point: 5.1199

>T268721 WP_271876320.1 NZ_CP116477:c889726-889421 [Pectobacterium sp. A5351]
MQFIVYQYKRASHYKMFVDVQSDIVETPKRRMVIPFIESHHLSEKVNKTLFPLIRINDEDYRLMTTELSSVPVEVMGEVI
ADLSDCANEIKDAINLMFWGI

Download         Length: 306 bp

Antitoxin


Download         Length: 73 a.a.        Molecular weight: 8246.24 Da        Isoelectric Point: 7.2038

>AT268721 WP_271876323.1 NZ_CP116477:c889947-889729 [Pectobacterium sp. A5351]
MKHRISVTVDKDNYQVLSTAGVNISGLVNDAIGKEARRIKVEEWKKESREGMEEVARFIAQHGSFADENRNW

Download         Length: 219 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References