Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/Cpta(toxin)
Location 668869..669529 Replicon chromosome
Accession NZ_CP116477
Organism Pectobacterium sp. A5351

Toxin (Protein)


Gene name cptA Uniprot ID -
Locus tag O1Q74_RS03125 Protein ID WP_271876037.1
Coordinates 669155..669529 (+) Length 125 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID C6D8Y5
Locus tag O1Q74_RS03120 Protein ID WP_012773340.1
Coordinates 668869..669135 (+) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
O1Q74_RS03100 (O1Q74_03100) 664885..665889 - 1005 WP_271876033.1 LacI family DNA-binding transcriptional regulator -
O1Q74_RS03105 (O1Q74_03105) 665944..666552 - 609 WP_271876034.1 HD domain-containing protein -
O1Q74_RS03110 (O1Q74_03110) 666931..667578 + 648 WP_271876035.1 hemolysin III family protein -
O1Q74_RS03115 (O1Q74_03115) 667632..668633 - 1002 WP_271876036.1 tRNA-modifying protein YgfZ -
O1Q74_RS03120 (O1Q74_03120) 668869..669135 + 267 WP_012773340.1 FAD assembly factor SdhE Antitoxin
O1Q74_RS03125 (O1Q74_03125) 669155..669529 + 375 WP_271876037.1 protein YgfX Toxin
O1Q74_RS03130 (O1Q74_03130) 669598..670533 + 936 WP_271876038.1 23S rRNA (adenine(1618)-N(6))-methyltransferase RlmF -
O1Q74_RS03135 (O1Q74_03135) 670583..670906 - 324 WP_271876039.1 hypothetical protein -
O1Q74_RS03140 (O1Q74_03140) 670935..671453 - 519 WP_271876040.1 flavodoxin FldB -
O1Q74_RS03145 (O1Q74_03145) 671615..672940 - 1326 WP_271876041.1 MFS transporter -
O1Q74_RS03150 (O1Q74_03150) 673252..674151 + 900 WP_271876042.1 site-specific tyrosine recombinase XerD -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Inner membrane protein YgfX

(2-119)

Antitoxin

Flavinator of succinate dehydrogenase

(8-79)


Sequences

Toxin        


Download         Length: 125 a.a.        Molecular weight: 14737.42 Da        Isoelectric Point: 10.7139

>T268719 WP_271876037.1 NZ_CP116477:669155-669529 [Pectobacterium sp. A5351]
MQLLSLVVHGLLVLLILLAPWPDGYAWLWLCLVTMVMFGFIRSQRNIKSRQGEIVLLSETTLNWRQQEWQIVKRPWLLKN
GVLLSLQTVNGKDRQQLWLASDSMGNDEWRHLRQLLLQQKYWAR

Download         Length: 375 bp

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 10465.94 Da        Isoelectric Point: 6.2223

>AT268719 WP_012773340.1 NZ_CP116477:668869-669135 [Pectobacterium sp. A5351]
MEIDNKSRIHWACRRGMRELDIAIMPFFEHDYDTLSDSDKRTFVRLLQSDDPDLFNWLMNHGEPKDGELKRMISLIQTRN
KDRGPVAM

Download         Length: 267 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB A0A7W2E501

References