Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/LOTUS_5_Limkain_b1-Phd
Location 1862369..1863042 Replicon chromosome
Accession NZ_CP116458
Organism Acidithiobacillus ferriphilus strain YL25

Toxin (Protein)


Gene name vapB Uniprot ID -
Locus tag PJU76_RS09385 Protein ID WP_271779317.1
Coordinates 1862369..1862791 (-) Length 141 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag PJU76_RS09390 Protein ID WP_271779318.1
Coordinates 1862788..1863042 (-) Length 85 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PJU76_RS09360 (PJU76_09360) 1858120..1858326 - 207 WP_271779312.1 hypothetical protein -
PJU76_RS09365 (PJU76_09365) 1858454..1858780 - 327 WP_271779313.1 EAL domain-containing protein -
PJU76_RS09370 (PJU76_09370) 1859087..1860127 + 1041 WP_271779314.1 extracellular solute-binding protein -
PJU76_RS09375 (PJU76_09375) 1860225..1861553 + 1329 WP_271779315.1 hypothetical protein -
PJU76_RS09380 (PJU76_09380) 1861692..1861898 + 207 WP_271779316.1 TOBE domain-containing protein -
PJU76_RS09385 (PJU76_09385) 1862369..1862791 - 423 WP_271779317.1 type II toxin-antitoxin system VapC family toxin Toxin
PJU76_RS09390 (PJU76_09390) 1862788..1863042 - 255 WP_271779318.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
PJU76_RS09395 (PJU76_09395) 1863354..1867472 + 4119 WP_271779319.1 DEAD/DEAH box helicase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(3-121)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(4-66)


Sequences

Toxin        


Download         Length: 141 a.a.        Molecular weight: 15439.84 Da        Isoelectric Point: 6.4788

>T268712 WP_271779317.1 NZ_CP116458:c1862791-1862369 [Acidithiobacillus ferriphilus]
VRYLLDTCVLSELVKKHPDPRVVTWVDAREAVGFLSVLTLGELQKGVAKLVDGDKRSMLQDWIDVDLRGRFVGRILPVNE
HIASAWGGITGAAEQRGEKLPAIDSLLAATALVHHLTVATRNIVDLQRCQVPVVDPWDQT

Download         Length: 423 bp

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 9522.64 Da        Isoelectric Point: 6.0642

>AT268712 WP_271779318.1 NZ_CP116458:c1863042-1862788 [Acidithiobacillus ferriphilus]
MNTQWPLQEARNHLSDVVKRARNDGPQTITLHGEPAVVVLSVEQFRTLTRPNQTLSEFLANSPLRGLDLEVERDHHDVGR
DVSL

Download         Length: 255 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References