Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relE-parD/RelE-RHH
Location 407658..408229 Replicon chromosome
Accession NZ_CP116458
Organism Acidithiobacillus ferriphilus strain YL25

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag PJU76_RS01955 Protein ID WP_271780261.1
Coordinates 407945..408229 (+) Length 95 a.a.

Antitoxin (Protein)


Gene name parD Uniprot ID -
Locus tag PJU76_RS01950 Protein ID WP_271780260.1
Coordinates 407658..407945 (+) Length 96 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PJU76_RS01920 (PJU76_01920) 402714..402863 - 150 WP_009568703.1 hypothetical protein -
PJU76_RS01925 (PJU76_01925) 402862..403089 + 228 WP_009568705.1 DUF6290 family protein -
PJU76_RS01930 (PJU76_01930) 403430..403975 - 546 WP_271780257.1 hypothetical protein -
PJU76_RS01935 (PJU76_01935) 404303..404728 - 426 WP_271780258.1 type II toxin-antitoxin system HicB family antitoxin -
PJU76_RS01940 (PJU76_01940) 405232..406323 - 1092 WP_271780259.1 SDR family oxidoreductase -
PJU76_RS01945 (PJU76_01945) 406454..406933 - 480 WP_215849195.1 rhodanese-like domain-containing protein -
PJU76_RS01950 (PJU76_01950) 407658..407945 + 288 WP_271780260.1 hypothetical protein Antitoxin
PJU76_RS01955 (PJU76_01955) 407945..408229 + 285 WP_271780261.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
PJU76_RS01960 (PJU76_01960) 408714..409415 - 702 WP_271780262.1 hypothetical protein -
PJU76_RS01965 (PJU76_01965) 409645..409767 - 123 WP_271780263.1 hypothetical protein -
PJU76_RS01970 (PJU76_01970) 410064..410672 - 609 WP_271780264.1 restriction endonuclease -
PJU76_RS01975 (PJU76_01975) 411102..412574 - 1473 WP_271780265.1 DUF2971 domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Integrative and Conjugative Element - - 397102..442556 45454


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-89)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 95 a.a.        Molecular weight: 10781.46 Da        Isoelectric Point: 9.5909

>T268707 WP_271780261.1 NZ_CP116458:407945-408229 [Acidithiobacillus ferriphilus]
MKLFWTPEAIQDRDNIYDHIEADNPAAALALDNLFSKKADRLVDHPGQGRPGRIVGTRELVAHRNYILVYDLAKDLVRVL
RVLHAARQWPPVKM

Download         Length: 285 bp

Antitoxin


Download         Length: 96 a.a.        Molecular weight: 10810.10 Da        Isoelectric Point: 8.9913

>AT268707 WP_271780260.1 NZ_CP116458:407658-407945 [Acidithiobacillus ferriphilus]
MSEATFTFRVDEALKTEFSTAAKARDRSGAQLLRDFMREFVQQQQEAAAHDTWFRRQVQMGLDSANAGNLVPAAEVEARF
AARRMATRRRLEASE

Download         Length: 288 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References