Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relE-dinJ/YafQ-RelB
Location 301962..302487 Replicon chromosome
Accession NZ_CP116458
Organism Acidithiobacillus ferriphilus strain YL25

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag PJU76_RS01430 Protein ID WP_271780174.1
Coordinates 302209..302487 (+) Length 93 a.a.

Antitoxin (Protein)


Gene name dinJ Uniprot ID -
Locus tag PJU76_RS01425 Protein ID WP_271780173.1
Coordinates 301962..302222 (+) Length 87 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PJU76_RS01405 (PJU76_01405) 297400..299154 + 1755 WP_271780170.1 penicillin-binding protein 2 -
PJU76_RS01410 (PJU76_01410) 299151..299462 + 312 WP_215849740.1 hypothetical protein -
PJU76_RS01415 (PJU76_01415) 299455..299778 + 324 WP_271780171.1 hypothetical protein -
PJU76_RS01420 (PJU76_01420) 299775..301640 - 1866 WP_271780172.1 ATP-binding cassette domain-containing protein -
PJU76_RS01425 (PJU76_01425) 301962..302222 + 261 WP_271780173.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
PJU76_RS01430 (PJU76_01430) 302209..302487 + 279 WP_271780174.1 type II toxin-antitoxin system YafQ family toxin Toxin
PJU76_RS01435 (PJU76_01435) 303079..303264 + 186 WP_271780175.1 hypothetical protein -
PJU76_RS01440 (PJU76_01440) 303395..304306 - 912 WP_271780176.1 hypothetical protein -
PJU76_RS01445 (PJU76_01445) 304484..304738 - 255 WP_271780177.1 DUF2442 domain-containing protein -
PJU76_RS01450 (PJU76_01450) 304771..305031 - 261 WP_271780178.1 DUF4160 domain-containing protein -
PJU76_RS01455 (PJU76_01455) 305130..305480 - 351 WP_064220135.1 DUF4870 domain-containing protein -
PJU76_RS01460 (PJU76_01460) 305673..305813 - 141 Protein_287 IS3 family transposase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, YafQ-like toxin

(2-90)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(1-70)


Sequences

Toxin        


Download         Length: 93 a.a.        Molecular weight: 10621.23 Da        Isoelectric Point: 8.9489

>T268706 WP_271780174.1 NZ_CP116458:302209-302487 [Acidithiobacillus ferriphilus]
MRTTKQTSQFKRDLKRESKGPYRKSLQEGFVALIEALAADLVLDQKYLDHPLSGDWIDHRDCHFKPDLVLIYRKTEGVLQ
LVRLGSHSELGL

Download         Length: 279 bp

Antitoxin


Download         Length: 87 a.a.        Molecular weight: 9528.00 Da        Isoelectric Point: 4.6263

>AT268706 WP_271780173.1 NZ_CP116458:301962-302222 [Acidithiobacillus ferriphilus]
MSANAVVRARIDEHIKEEATVVLAAMGLTVSDAFRLMLTRVAREKLLPFDPLVPNEKTIEAMKEARQGHLETVTLQDLQA
VLDADD

Download         Length: 261 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References