268702

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PP_4151-4152/excise(antitoxin)
Location 86626..87662 Replicon plasmid unnamed4
Accession NZ_CP116427
Organism Sulfitobacter faviae strain SCSIO W_1865

Toxin (Protein)


Gene name PP_4152 Uniprot ID A0A386TJD0
Locus tag PL336_RS19555 Protein ID WP_065331084.1
Coordinates 87087..87662 (+) Length 192 a.a.

Antitoxin (Protein)


Gene name PP_4151 Uniprot ID A0A940EE17
Locus tag PL336_RS19550 Protein ID WP_065331085.1
Coordinates 86626..87090 (+) Length 155 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PL336_RS19525 (PL336_19525) 82851..83108 + 258 WP_064225038.1 type II toxin-antitoxin system ParD family antitoxin -
PL336_RS19530 (PL336_19530) 83105..83440 + 336 WP_064225037.1 type II toxin-antitoxin system RelE/ParE family toxin -
PL336_RS19535 (PL336_19535) 83447..84562 - 1116 WP_065331088.1 tyrosine-type recombinase/integrase -
PL336_RS19540 (PL336_19540) 84719..85603 + 885 WP_065331087.1 DUF1403 family protein -
PL336_RS19545 (PL336_19545) 85606..86220 + 615 WP_065331086.1 SMC-Scp complex subunit ScpB -
PL336_RS19550 (PL336_19550) 86626..87090 + 465 WP_065331085.1 helix-turn-helix domain-containing protein Antitoxin
PL336_RS19555 (PL336_19555) 87087..87662 + 576 WP_065331084.1 PIN domain-containing protein Toxin
PL336_RS19560 (PL336_19560) 87782..87937 - 156 Protein_75 nucleotidyl transferase AbiEii/AbiGii toxin family protein -
PL336_RS19565 (PL336_19565) 88035..88400 + 366 WP_065331083.1 transposase -
PL336_RS19570 (PL336_19570) 88397..88744 + 348 WP_017467473.1 IS66 family insertion sequence element accessory protein TnpB -
PL336_RS19575 (PL336_19575) 88814..90517 + 1704 WP_065331082.1 IS66 family transposase -
PL336_RS19580 (PL336_19580) 90550..90879 + 330 WP_017467358.1 quaternary ammonium compound efflux SMR transporter SugE -
PL336_RS19585 (PL336_19585) 90939..91280 - 342 WP_065331081.1 hypothetical protein -
PL336_RS19590 (PL336_19590) 91296..91424 - 129 WP_007120576.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..103482 103482


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(11-115)

Antitoxin

Helix-turn-helix domain, group 17

(85-133)


Sequences

Toxin        


Download         Length: 192 a.a.        Molecular weight: 20927.78 Da        Isoelectric Point: 4.5612

>T268702 WP_065331084.1 NZ_CP116427:87087-87662 [Sulfitobacter faviae]
MSRHADRFTALLDACVLGGALRRNMLLSLAEAGLFRPRWSSRILDETQKAITQITKGETDGSRQRAAIEAAFPEALVTGY
EIFEDKLALPDPNDNHVLAAAIATSASVIVTDNLADFPSAVLDPHSIQAISADDFIADTIELDPSEAIMALRRMRERFKN
PALDVATLIHKSEAQGLLQVATFMDEYQSFL

Download         Length: 576 bp

Antitoxin


Download         Length: 155 a.a.        Molecular weight: 17094.54 Da        Isoelectric Point: 4.7979

>AT268702 WP_065331085.1 NZ_CP116427:86626-87090 [Sulfitobacter faviae]
MNALRKEAFFDRLPDEVEIKNAEQLRTIVASQIKEGEPTKLSLALEDGEVRTVTLAPALTASLLEVLRLVSSGRGFRMIP
VESELTTQQAADLLNVSRPFLVKLLEEGEIPFAKTGRHRRVRADDLFAYKEKRDASRSDALSDLAAMDAEEGLV

Download         Length: 465 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A386TJD0

Antitoxin

Source ID Structure

References