Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/PIN-MazE
Location 100625..101237 Replicon plasmid unnamed3
Accession NZ_CP116426
Organism Sulfitobacter faviae strain SCSIO W_1865

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag PL336_RS18755 Protein ID WP_028288627.1
Coordinates 100842..101237 (+) Length 132 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID A0A921TG38
Locus tag PL336_RS18750 Protein ID WP_009503866.1
Coordinates 100625..100852 (+) Length 76 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PL336_RS18735 (PL336_18735) 96882..98093 - 1212 WP_050525470.1 plasmid replication protein RepC -
PL336_RS18740 (PL336_18740) 98307..99239 - 933 WP_028288626.1 plasmid partitioning protein RepB -
PL336_RS18745 (PL336_18745) 99223..100416 - 1194 WP_009503867.1 plasmid partitioning protein RepA -
PL336_RS18750 (PL336_18750) 100625..100852 + 228 WP_009503866.1 AbrB/MazE/SpoVT family DNA-binding domain-containing protein Antitoxin
PL336_RS18755 (PL336_18755) 100842..101237 + 396 WP_028288627.1 PIN domain-containing protein Toxin
PL336_RS18760 (PL336_18760) 101316..102200 - 885 WP_028288628.1 recombinase family protein -
PL336_RS18765 (PL336_18765) 102430..103497 + 1068 WP_088635931.1 hypothetical protein -
PL336_RS18770 (PL336_18770) 103713..104303 + 591 WP_088635923.1 L,D-transpeptidase -
PL336_RS18775 (PL336_18775) 104387..104965 + 579 WP_009815505.1 L,D-transpeptidase -
PL336_RS18780 (PL336_18780) 105029..105786 + 758 WP_088635922.1 IS5 family transposase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..182751 182751


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(5-113)

Antitoxin

Antitoxin PemI-like

(2-47)


Sequences

Toxin        


Download         Length: 132 a.a.        Molecular weight: 14212.23 Da        Isoelectric Point: 4.1653

>T268701 WP_028288627.1 NZ_CP116426:100842-101237 [Sulfitobacter faviae]
MSVEFADTNVVLYLLDDGPKADRAEVILGQGPRISVQVLNESLVNCRRKAGLGWEEAAAFLEGVRALCPVEDLTVQTHDV
GRALAERYGFSIYDAMIVASALVAGCTTLWSEDMQDGLLVEGQLRIVNPFA

Download         Length: 396 bp

Antitoxin


Download         Length: 76 a.a.        Molecular weight: 8535.79 Da        Isoelectric Point: 11.0482

>AT268701 WP_009503866.1 NZ_CP116426:100625-100852 [Sulfitobacter faviae]
MQVAKWGNSLAVRLPAELVRELGLKEGDQIDLVKDDGRVRVRRLARADEVLTGLRRFRGKLSAAERLSRDDAHER

Download         Length: 228 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References