Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RelE-RelB
Location 76862..77423 Replicon plasmid unnamed3
Accession NZ_CP116426
Organism Sulfitobacter faviae strain SCSIO W_1865

Toxin (Protein)


Gene name relE Uniprot ID A0A917AH87
Locus tag PL336_RS18625 Protein ID WP_071974127.1
Coordinates 76862..77137 (-) Length 92 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID A0A1N7QLX2
Locus tag PL336_RS18630 Protein ID WP_044353023.1
Coordinates 77124..77423 (-) Length 100 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PL336_RS18615 (PL336_18615) 71980..72366 - 387 WP_271690410.1 hypothetical protein -
PL336_RS18620 (PL336_18620) 72493..76755 - 4263 WP_271690411.1 strawberry notch family protein -
PL336_RS18625 (PL336_18625) 76862..77137 - 276 WP_071974127.1 type II toxin-antitoxin system mRNA interferase toxin, RelE/StbE family Toxin
PL336_RS18630 (PL336_18630) 77124..77423 - 300 WP_044353023.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
PL336_RS18635 (PL336_18635) 77528..78184 - 657 WP_271690412.1 hypothetical protein -
PL336_RS18640 (PL336_18640) 78184..78777 - 594 WP_271690413.1 regulator -
PL336_RS18645 (PL336_18645) 78852..80819 - 1968 WP_271690414.1 ParB/RepB/Spo0J family partition protein -
PL336_RS18650 (PL336_18650) 80977..81366 - 390 WP_271690415.1 DUF3768 domain-containing protein -
PL336_RS18655 (PL336_18655) 81454..81663 - 210 WP_271690416.1 DUF6330 family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..182751 182751


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-90)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(5-54)


Sequences

Toxin        


Download         Length: 92 a.a.        Molecular weight: 10388.92 Da        Isoelectric Point: 4.5837

>T268700 WP_071974127.1 NZ_CP116426:c77137-76862 [Sulfitobacter faviae]
MPNLEWKATAIADLLAIIDYISDDNPDAAQVLKDEIEHKTSLLPERPQMYRAGRVDGTREMVVRPNYIVVYAESPEMVTI
LRVLHAAQQWP

Download         Length: 276 bp

Antitoxin


Download         Length: 100 a.a.        Molecular weight: 10462.91 Da        Isoelectric Point: 5.6448

>AT268700 WP_044353023.1 NZ_CP116426:c77423-77124 [Sulfitobacter faviae]
MPAQTSMLHVRVDDQLKAQASDALAGVGLTLSDAVRILLTRVAAEGGLPAGLTADPDAYDAWFRAKVQEALDDPRPTTPH
AKAMQDAQALIDGKRLAKS

Download         Length: 300 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB A0A1N7QLX2

References