Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RelE-RelB
Location 27557..28118 Replicon plasmid unnamed3
Accession NZ_CP116422
Organism Sulfitobacter faviae strain SCSIO W_1866

Toxin (Protein)


Gene name relE Uniprot ID A0A917AH87
Locus tag PL335_RS17460 Protein ID WP_071974127.1
Coordinates 27843..28118 (+) Length 92 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID A0A1N7QLX2
Locus tag PL335_RS17455 Protein ID WP_044353023.1
Coordinates 27557..27856 (+) Length 100 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PL335_RS17430 (PL335_17430) 22887..23312 + 426 WP_219002066.1 response regulator -
PL335_RS17435 (PL335_17435) 23492..23881 + 390 WP_271694213.1 DUF3768 domain-containing protein -
PL335_RS17440 (PL335_17440) 24040..26022 + 1983 WP_271694214.1 ParB/RepB/Spo0J family partition protein -
PL335_RS17445 (PL335_17445) 26099..26692 + 594 WP_271694215.1 regulator -
PL335_RS17450 (PL335_17450) 26796..27452 + 657 WP_271694216.1 hypothetical protein -
PL335_RS17455 (PL335_17455) 27557..27856 + 300 WP_044353023.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
PL335_RS17460 (PL335_17460) 27843..28118 + 276 WP_071974127.1 type II toxin-antitoxin system mRNA interferase toxin, RelE/StbE family Toxin
PL335_RS17465 (PL335_17465) 28225..32498 + 4274 Protein_29 strawberry notch family protein -
PL335_RS17470 (PL335_17470) 32514..32867 + 354 WP_271694218.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..100908 100908


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-90)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(5-54)


Sequences

Toxin        


Download         Length: 92 a.a.        Molecular weight: 10388.92 Da        Isoelectric Point: 4.5837

>T268699 WP_071974127.1 NZ_CP116422:27843-28118 [Sulfitobacter faviae]
MPNLEWKATAIADLLAIIDYISDDNPDAAQVLKDEIEHKTSLLPERPQMYRAGRVDGTREMVVRPNYIVVYAESPEMVTI
LRVLHAAQQWP

Download         Length: 276 bp

Antitoxin


Download         Length: 100 a.a.        Molecular weight: 10462.91 Da        Isoelectric Point: 5.6448

>AT268699 WP_044353023.1 NZ_CP116422:27557-27856 [Sulfitobacter faviae]
MPAQTSMLHVRVDDQLKAQASDALAGVGLTLSDAVRILLTRVAAEGGLPAGLTADPDAYDAWFRAKVQEALDDPRPTTPH
AKAMQDAQALIDGKRLAKS

Download         Length: 300 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB A0A1N7QLX2

References