Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-VapB
Location 7672982..7673477 Replicon chromosome
Accession NZ_CP116413
Organism Crossiella sp. CA-258035

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag N8J89_RS34500 Protein ID WP_283661134.1
Coordinates 7672982..7673245 (-) Length 88 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag N8J89_RS34505 Protein ID WP_283661135.1
Coordinates 7673256..7673477 (-) Length 74 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
N8J89_RS34475 (N8J89_34465) 7668164..7669582 + 1419 WP_283661129.1 alpha/beta fold hydrolase -
N8J89_RS34480 (N8J89_34470) 7669594..7670616 + 1023 WP_283661130.1 histidine kinase -
N8J89_RS34485 (N8J89_34475) 7670613..7671245 + 633 WP_283661131.1 response regulator transcription factor -
N8J89_RS34490 (N8J89_34480) 7671242..7672018 - 777 WP_283661132.1 hypothetical protein -
N8J89_RS34495 (N8J89_34485) 7672073..7672957 + 885 WP_283661133.1 Lrp/AsnC family transcriptional regulator -
N8J89_RS34500 (N8J89_34490) 7672982..7673245 - 264 WP_283661134.1 hypothetical protein Toxin
N8J89_RS34505 (N8J89_34495) 7673256..7673477 - 222 WP_283661135.1 type II toxin-antitoxin system VapB family antitoxin Antitoxin
N8J89_RS34510 (N8J89_34500) 7673485..7674222 - 738 WP_283661136.1 3-keto-5-aminohexanoate cleavage protein -
N8J89_RS34515 (N8J89_34505) 7674232..7674732 - 501 WP_283661137.1 GNAT family N-acetyltransferase -
N8J89_RS34520 (N8J89_34510) 7674701..7676842 - 2142 WP_283661138.1 NAD-dependent DNA ligase LigA -
N8J89_RS34525 (N8J89_34515) 7676883..7677554 - 672 WP_252485001.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Bacterial antitoxin of type II TA system, VapB

(3-38)


Sequences

Toxin        


Download         Length: 88 a.a.        Molecular weight: 9343.90 Da        Isoelectric Point: 7.2780

>T268698 WP_283661134.1 NZ_CP116413:c7673245-7672982 [Crossiella sp. CA-258035]
MRDPGSLATTEPVILEVRSGLDGFRLIRLDQALSSLTLLGVDPAVDFHTGSELYRAVRKTGHTVRSMMDCLIAAVALRTG
AVLVHAL

Download         Length: 264 bp

Antitoxin


Download         Length: 74 a.a.        Molecular weight: 8311.38 Da        Isoelectric Point: 4.2584

>AT268698 WP_283661135.1 NZ_CP116413:c7673477-7673256 [Crossiella sp. CA-258035]
MARTTIDIDEELVDEAMRRYGLRTKKDAVDFALRRLVGPKITTEELLSLEGIGWEGDLEQMRADNPECAWNSA

Download         Length: 222 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References