Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/NGN_SP-Phd
Location 3523510..3524195 Replicon chromosome
Accession NZ_CP116413
Organism Crossiella sp. CA-258035

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag N8J89_RS16270 Protein ID WP_283665186.1
Coordinates 3523779..3524195 (+) Length 139 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag N8J89_RS16265 Protein ID WP_283665185.1
Coordinates 3523510..3523782 (+) Length 91 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
N8J89_RS16245 (N8J89_16245) 3519516..3519911 + 396 WP_283665181.1 winged helix-turn-helix transcriptional regulator -
N8J89_RS16250 (N8J89_16250) 3520099..3521448 - 1350 WP_283665182.1 hypothetical protein -
N8J89_RS16255 (N8J89_16255) 3521476..3521937 - 462 WP_283665183.1 hypothetical protein -
N8J89_RS16260 (N8J89_16260) 3522558..3523436 + 879 WP_283665184.1 helix-turn-helix transcriptional regulator -
N8J89_RS16265 (N8J89_16265) 3523510..3523782 + 273 WP_283665185.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
N8J89_RS16270 (N8J89_16270) 3523779..3524195 + 417 WP_283665186.1 type II toxin-antitoxin system VapC family toxin Toxin
N8J89_RS16275 (N8J89_16275) 3524246..3524728 + 483 WP_283665187.1 hypothetical protein -
N8J89_RS16280 (N8J89_16280) 3524799..3526145 - 1347 WP_283665188.1 hypothetical protein -
N8J89_RS16285 (N8J89_16285) 3526393..3526929 + 537 WP_283665189.1 hypothetical protein -
N8J89_RS16290 (N8J89_16290) 3527159..3527638 + 480 WP_283665190.1 helix-turn-helix domain-containing protein -
N8J89_RS16295 (N8J89_16295) 3527993..3528427 + 435 WP_283665191.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Genomic island - - 3496993..3535217 38224


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(4-120)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(9-71)


Sequences

Toxin        


Download         Length: 139 a.a.        Molecular weight: 15088.33 Da        Isoelectric Point: 4.9008

>T268697 WP_283665186.1 NZ_CP116413:3523779-3524195 [Crossiella sp. CA-258035]
MSFLLDTNIVSEIRKKNPNRGVAEWFDSVSASELFVSVLVVGEIRQGIERLARRDSAQAAVFEQWLGRLLEVYGDRIVPV
TAEVAEAWGRLNVPDPVPVVDGLMAATALVRGWTLVTRNRADVAATGVRLLDPFTGAV

Download         Length: 417 bp

Antitoxin


Download         Length: 91 a.a.        Molecular weight: 10005.31 Da        Isoelectric Point: 4.6697

>AT268697 WP_283665185.1 NZ_CP116413:3523510-3523782 [Crossiella sp. CA-258035]
VVVDMAGHWQLQDAKQRFSELIRLVKAEGPQIVTRSGEEVAVVIDIAEYRRLRGDGRDFKDFLRSAPELDALEITRSAAP
ARVVDLGDDG

Download         Length: 273 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References