268686

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) yfjZ-ypjF/CbtA-CbeA
Location 1202033..1202691 Replicon chromosome
Accession NZ_CP116411
Organism Escherichia coli strain HH45

Toxin (Protein)


Gene name ypjF Uniprot ID -
Locus tag PL330_RS05785 Protein ID WP_271710746.1
Coordinates 1202033..1202353 (-) Length 107 a.a.

Antitoxin (Protein)


Gene name yfjZ Uniprot ID -
Locus tag PL330_RS05790 Protein ID WP_105609402.1
Coordinates 1202374..1202691 (-) Length 106 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PL330_RS05770 (1197455) 1197455..1198903 - 1449 WP_000772847.1 NADP-dependent succinate-semialdehyde dehydrogenase -
PL330_RS05775 (1198926) 1198926..1200194 - 1269 WP_000271942.1 L-2-hydroxyglutarate oxidase -
PL330_RS05780 (1200214) 1200214..1201191 - 978 WP_000993087.1 glutarate dioxygenase GlaH -
PL330_RS05785 (1202033) 1202033..1202353 - 321 WP_271710746.1 TA system toxin CbtA family protein Toxin
PL330_RS05790 (1202374) 1202374..1202691 - 318 WP_105609402.1 type IV toxin-antitoxin system YeeU family antitoxin Antitoxin
PL330_RS05795 (1202767) 1202767..1202931 - 165 WP_072025243.1 DUF987 family protein -
PL330_RS05800 (1202940) 1202940..1203416 - 477 WP_047620722.1 RadC family protein -
PL330_RS05805 (1203432) 1203432..1203946 - 515 Protein_1135 antirestriction protein -
PL330_RS05810 (1203977) 1203977..1204159 - 183 Protein_1136 DUF905 family protein -
PL330_RS05815 (1204315) 1204315..1205382 - 1068 WP_001683202.1 hypothetical protein -
PL330_RS05820 (1205673) 1205673..1206384 - 712 Protein_1138 DeoR family transcriptional regulator -
PL330_RS05825 (1206603) 1206603..1207410 - 808 Protein_1139 DUF932 domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

CbtA toxin of type IV toxin-antitoxin system

(1-104)

Antitoxin

Antitoxin CbeA

(5-104)


Sequences

Toxin        


Download         Length: 107 a.a.        Molecular weight: 12131.32 Da        Isoelectric Point: 10.2638

>T268686 WP_271710746.1 NZ_CP116411:c1202353-1202033 [Escherichia coli]
MKTLPATISRAAKPCLSPVAVWQMLLTRLLEKHYGLTLNDTPFCDETVIQEHIDAGITLANAVNFLVKKYELVRIDRKGF
SWQKQSPFITAVDILKARRAMREMRT

Download         Length: 321 bp

Antitoxin


Download         Length: 106 a.a.        Molecular weight: 12008.67 Da        Isoelectric Point: 6.9462

>AT268686 WP_105609402.1 NZ_CP116411:c1202691-1202374 [Escherichia coli]
MSNITWGLQRDITPRLGARLVQEGNRLHYLADRANITDKFSDAECLKLDVAFPHFIRQMESMLTTSEMNPRHAHCVTLYH
NGFTCEADTLGSCGYVYIAIYPTQR

Download         Length: 318 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References