Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) pasB-mqsA/RelE-MqsA
Location 1814036..1814736 Replicon chromosome
Accession NZ_CP116398
Organism Methylomonas sp. EFPC3

Toxin (Protein)


Gene name pasB Uniprot ID -
Locus tag PL263_RS08090 Protein ID WP_256611152.1
Coordinates 1814479..1814736 (-) Length 86 a.a.

Antitoxin (Protein)


Gene name mqsA Uniprot ID -
Locus tag PL263_RS08085 Protein ID WP_278212524.1
Coordinates 1814036..1814437 (-) Length 134 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PL263_RS08050 (PL263_08050) 1809346..1809675 + 330 WP_278212518.1 hypothetical protein -
PL263_RS08055 (PL263_08055) 1809747..1810412 - 666 WP_278212519.1 hypothetical protein -
PL263_RS08060 (PL263_08060) 1810723..1811679 + 957 WP_278212520.1 matrixin family metalloprotease -
PL263_RS08065 (PL263_08065) 1811707..1812330 - 624 WP_278212521.1 hypothetical protein -
PL263_RS08070 (PL263_08070) 1812302..1812862 - 561 WP_278212522.1 exosortase family protein XrtM -
PL263_RS08075 1813031..1813135 + 105 Protein_1599 integrase -
PL263_RS08080 (PL263_08075) 1813219..1813893 - 675 WP_278212523.1 hypothetical protein -
PL263_RS08085 (PL263_08080) 1814036..1814437 - 402 WP_278212524.1 type II toxin-antitoxin system MqsA family antitoxin Antitoxin
PL263_RS08090 (PL263_08085) 1814479..1814736 - 258 WP_256611152.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
PL263_RS08095 (PL263_08090) 1814726..1814923 - 198 WP_140912349.1 hypothetical protein -
PL263_RS08105 (PL263_08100) 1815297..1816142 - 846 WP_278212525.1 sulfite exporter TauE/SafE family protein -
PL263_RS08110 (PL263_08105) 1816143..1818593 - 2451 WP_278212526.1 heavy metal translocating P-type ATPase -
PL263_RS08115 (PL263_08110) 1818665..1819276 - 612 WP_140912351.1 hypothetical protein -
PL263_RS08120 (PL263_08115) 1819374..1819670 - 297 WP_186289570.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(3-84)

Antitoxin

Zinc finger, MqsA-type

(3-48)


Sequences

Toxin        


Download         Length: 86 a.a.        Molecular weight: 9873.54 Da        Isoelectric Point: 9.6735

>T268638 WP_256611152.1 NZ_CP116398:c1814736-1814479 [Methylomonas sp. EFPC3]
MTYSVVFKPSAEKAFSKLPNEIQKRLYAAACDLAENPRPPGFKKLHGVDDLYRIRVGDYRMVYTIEDCQLKILVVAIGHR
REIYR

Download         Length: 258 bp

Antitoxin


Download         Length: 134 a.a.        Molecular weight: 14566.83 Da        Isoelectric Point: 5.7671

>AT268638 WP_278212524.1 NZ_CP116398:c1814437-1814036 [Methylomonas sp. EFPC3]
MKCPSCAVGELVHDTRDVPYTYKGGTTVIPLVTGDFCPACDEVITDAEESKRTMALMLEFNKQVNASIVDPGFIASVRKK
LALDQREASEIFGGGINAFSRYENGKTKPPLALVKLLKVLDRHPELLDEIRAA

Download         Length: 402 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References