Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) /BrnT(toxin)
Location 221237..221729 Replicon chromosome
Accession NZ_CP116398
Organism Methylomonas sp. EFPC3

Toxin (Protein)


Gene name - Uniprot ID -
Locus tag PL263_RS01005 Protein ID WP_278211276.1
Coordinates 221466..221729 (-) Length 88 a.a.

Antitoxin (Protein)


Gene name - Uniprot ID -
Locus tag PL263_RS01000 Protein ID WP_278211275.1
Coordinates 221237..221476 (-) Length 80 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PL263_RS00975 (PL263_00975) 216495..218120 - 1626 WP_278211270.1 PASTA domain-containing protein -
PL263_RS00980 (PL263_00980) 218538..219197 + 660 WP_278211271.1 hypothetical protein -
PL263_RS00985 (PL263_00985) 219778..220305 + 528 WP_278211272.1 GGDEF domain-containing protein -
PL263_RS00990 (PL263_00990) 220408..220758 - 351 WP_278211273.1 hypothetical protein -
PL263_RS00995 (PL263_00995) 220828..221202 - 375 WP_278211274.1 hypothetical protein -
PL263_RS01000 (PL263_01000) 221237..221476 - 240 WP_278211275.1 CopG family antitoxin Antitoxin
PL263_RS01005 (PL263_01005) 221466..221729 - 264 WP_278211276.1 BrnT family toxin Toxin
PL263_RS01010 (PL263_01010) 221882..223819 - 1938 WP_278211277.1 molecular chaperone HtpG -
PL263_RS01015 (PL263_01015) 223945..225573 + 1629 WP_278211278.1 response regulator -
PL263_RS01020 (PL263_01020) 225576..226259 + 684 WP_278211279.1 HAMP domain-containing sensor histidine kinase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Ribonuclease toxin, BrnT, of type II toxin-antitoxin system

(6-81)

Antitoxin

CopG antitoxin

(1-69)


Sequences

Toxin        


Download         Length: 88 a.a.        Molecular weight: 10348.91 Da        Isoelectric Point: 10.3074

>T268637 WP_278211276.1 NZ_CP116398:c221729-221466 [Methylomonas sp. EFPC3]
MFKFEFDEAKSRSNLEKHGIDFIDAQVLWNDSRLLQIPAKTEDEPRFLVIGVIKRKHWSAVITYRGNRIRIISVRRSRAE
EVKLYES

Download         Length: 264 bp

Antitoxin


Download         Length: 80 a.a.        Molecular weight: 9150.30 Da        Isoelectric Point: 4.4432

>AT268637 WP_278211275.1 NZ_CP116398:c221476-221237 [Methylomonas sp. EFPC3]
MKAEEFEKQFDDDIDISDSLDLSQAQRIMQTQKRVNVDFPAWMIDSLDREAGRLGVTRQSVIKMWLAERLEKSSLSTNS

Download         Length: 240 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References